I have the same mutations. I will have to be on the same regimine once I get pregnant. I have 2 children, but those pregnancies went fine without any blood thinners, thank God. I did not know I had this condition then. I'm worried about it all too. Hopefully some people will respond because I'd like to hear some success stories! :)
I too have the mutations C677T and Prothombin mutation. I am 9 weeks along and taking 40mgs of Lovenox, 5mg Folic Acid, 100mg Vitamin B complex and a Low dose baby aspirin.
So far, I am past the time frames where I lost the last three pregnancies, but by no means do I feel I am out of the woods. Someone who could better address this is K10Road, Kris. She is nearly due and had 3 losses consecutively also until being put onto Lovenox and the same regimen as the rest of us.
I feel that her story is probably what forced me to get this test and get the same treatments. She is my god send, but also my best friend.
I will message her to get her to share with us as well.
In addition to anything I have mentioned, please keep in mind, that while I or others may have extensive knowledge in many areas, you should always seek professional medical advice from your own physician, as it pertains to medical conditions or concerns.
Good luck, and if you have any other questions that I can help you with, please feel free to message me directly.
MedHelp Genetics Community Leader;
Children - Special Needs Community Leader;
Down syndrome Community Leader & Ds Group Forum Founder/Moderator;
MTHFR Group Forum Founder/Moderator;
Pregnancy: June 2011 Community Leader
Hi ladies. Sorry I didn't see this sooner...just got Sandi's note. I'm not on MH as much as I should be anymore - just completely exhausted right about now as I am soooo close to the end as Sandi said!!
I have 2 boys, ages 3 and 5, and those pregnancies were completely textbook. Never had any issues to write about. May 2009, I was diagnosed with a blighted ovum at 12 weeks. That was devastating!!! My husband had just deployed to Iraq, and I totally didn't plan on getting pregnant right before he left, but I most definitely did NOT plan on losing a pregnancy while he was gone. It was terrible. He came home in October 2009, and I got pregnant again in November. I lost that pregnancy in mid-December 2009. I then got pregnant again in January/February sometime (pregnancy brain is not helping me remember right now), and I miscarried in the end of February 2010. I wasn't making it past like 6-7 weeks, and I wasn't seeing a heartbeat. FINALLY - after 3 consecutive losses - I got my midwives to do some testing. They checked off all kinds of things...but NOT MTHFR.
Well...I had been doing my research as to what can cause recurrent miscarriage, and I was leaning towards MTHFR for some reason - just based on other things I had experienced. So, I fibbed...lol...I called the midwife and told her that I was friends with someone at the lab and that they told me that typically when they test for all of these other things, they also test for MTHFR...so, she added it on. THANK GOD.
Sure enough, a few days later, I came back positive for homozygous MTHFR A1298C mutation. I had already been taking the low dose (baby) aspirin of 81mg. And I started the Folgard (similar to Metanx) right before the positive results. My midwife figured she could stop that medication if I didn't need it, but no harm in starting it a few days early. I was then sent to a perinatolgist recommended by my midwife. The first one I saw told me that no way in the world would he treat a subsequent pregnancy any differently and NO WAY would he prescribe lovenox. I called my midwife (who I LOVED) and asked her why in the world she sent me to this guy?? She said that she had spoken with them and was told that they would do lovenox. Needless to say, that perinatologist didn't like me too much after this (because I questioned him). Anyway, he conferred with his colleagues, and one of them said that most definitely she would treat me with lovenox if and when i got pregnant again. This was in March. Well....I didn't even have time to make another appointment!!!
I got pregnant again the first week of April. I got my BFP at 8 or 9 dpo, and I went in to see her IMMEDIATELY. She started me on lovenox the same day...30mg twice a day. She kept me on the baby aspirin and Folgard, which contained 4400mcg folic acid, in addition to my 800mcg that I get from my prenatals. I also take fish oil 1000mg twice a day as it has natural blood thinning properties.
I am now 34 1/2 weeks along, and we have a scheduled induction for 38 weeks. I absolutely cannot wait to meet my little man!!!
Thanks ladies. That makes me feel better. I am working with a high risk ob/gyn and he has been really supportive thankfully. After hearing so many stories of doctors who don't take this seriously enough, I feel grateful to have found him.
Thanks ladies i loved hearing all your journeys . I am in need of these stories becuase i feel like something can go wrong in a drop of a hat and you all keep me sane .. I am very thankful for this doctor i found he doesn't make me feel the need to question anything . He acutally started me on lovenox right after ovulation was confirmed instead of waiting for a confirmed pregnancy test.