I wondered if anyone gets mental changes? At age 12 the mental changes started and by age 21 the pain started in my lower back. At 24 they found Medullary Nephrocalcinosis on CT scan. My Nephrologist at the time said that, my pain couldn't possibly be from my kidneys and my "condition" wasn't something to worry about. He didn't say anything about a kidney disease and when I tried to get disability, I was told I didn't qualify. I am now 45 and have literally been in constant pain, exhausted, nauseated, dizzy, headaches, etc. I'm past frustration and was giving up hope but, I found this site and see now that, I am not alone in the pain factor. Hopefully, someone else goes through mental shifts too.