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Can someone help me translate my Brain MRI results please?

Hi there,

I'm a 34 year old female with a family history of MS. (Cousins).

I've recently been referred to a neurologist after 6-12 months of weird 'symptoms' happening to me. Mainly cognitive - I've been having trouble with memory and conversation since the start of the year. I have also had numbness in my left hand for a week or so, numbness in the face (right side for 24 hours), trouble with my vision - eye ball pain for 24 hours, pins and needles on right foot etc. Mainly it's memory and the numbness that's the issue. Not terrible, but enough to make me think 'what the hell?!'. So far it's all back to normal.

Anyway I got my MRI and here are the results - I was wondering if anyone could help me translate please!

Brain: In the deep peri-ventricular white matter particularly in the deep parietal region but also in the frontal region (maximal on the left) there are some foci of T2 hyperintense change which are immediately subependymal in relation to the left frontal horn. There is almost certainly a small lesion anteriorly at the calloso-septal interface. No definite posterior fossa disease is seen.

Conclusion: Cerebral appearance highly suggestive of demyelination.

(Cervico-Thoratic Region MRI had no evidence of cord lesion and Lumbar/Spine MRI came up clear also.

I would love to hear your thoughts/interpretation of my results!

Thanks so much :)
1 Responses
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987762 tn?1671273328
COMMUNITY LEADER
Hi and welcome,

Having a genetic susceptibility with MS is typically from a closer relationship than cousin's ie mother, father, brother, sister, the further removed from your genetic pool the lower the susceptibility.  Having cousin's with MS is suppose to be even less than if it was an aunt or uncle.

Unfortunately, though having said that, the small lesion anteriorly at the calloso-septal interface would place MS quite high on your list of possible causes because of that specific location having a higher association....

"A recent study [1] showed that lesions at the callosal-sept-tal interface (CSI) demonstrated by magnetic resonance imaging (MRI) were a sensitive (93 %) and highly specific (97 %) indicator of multiple sclerosis (MS)."
https://link.springer.com/article/10.1007/BF00588395

.....and one of the reasons why the radiologist states in his conclusion "Cerebral appearance highly suggestive of demyelination"

The diagnostic process can be stressful and take a long time, MS is diagnosed on a lot more than just the MRI evidence, there is some MRI evidence suggestive of MS but until all your test results are in, it's in your best interest to try to stay open minded to what might be going on.  

I hope that helps......JJ
Helpful - 0
3 Comments
Thanks so much for your detailed response! Have an appointment next week with my neurologist.
please let us know how your neuro appointment goes.....JJ
Will do!
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