Newly diagnosed with MS. On copaxone 40mg. First 3 shots were fine. Shots 4,5 about three hours after giving the injection my entire body starts aching, extreme chills (whole body jumping and teeth chattering), muscles cramping, fever (100.9-102.0), hands burning, headache. Reported it to Shared Solutions and they acted familiar with these symptoms. My neuro wasn't and said to try zyrtec and tylenol prior to injection. Also ran it by another neuro and he wasn't familiar with these symptoms. Last night I did the zyrtec and tylenol and same thing happened 3 1/2 hours after injection. It's so intense and painful. I also have Lupus and this reaction reminds me of a lupus flare. I don't think I can do this shot and I really want it to work. I'm nursing my baby and don't have any options besides this. Has anyone else experienced these extreme side effects?