Hi Lesley, i think your poll might be difficult for people to answer because muscle wastage and weight issues are generally two completely different types of issues.....
It's common to gain/loose weight because of medication side effects, loose weight from nutritional issues due to nausea, vomiting, swallowing dysfunction, gastric issues etc gain weight from low energy, life style, inactivity, limited mobility etc weight issues are generally thought to be a secondary or a comobid issue.
It's more common to have isolated muscle wastage or atrophy in a specific locations with MS eg right foot drop and right side calf atrophy but normal calf size on the left side etc all over muscle wastage/atrophy isn't typically a primary issue with MS. Muscle wasting or atrophy has a few different causes but in MS its generally two types a) secondary - ie disuse atrophy in which the muscles waste away due to lack of use, 2) primary - ie neurogenic atrophy which is caused by dysfunction of motor nerve fibers, signal etc causing muscle weakness, lack of muscle control and eventual wasting of the muscle.....
Hope that makes sense it's getting very late, and lol i've completely lost my thoughts sorry if i've mixed anything up....
Cheers.........JJ