I have been shadowing this site for a little over a month now and thought I'd chime in. I am a 33 year old woman with five kids. In the beginning of August, so, about 3 months ago, I noticed I had a headache that wasn't responding to painkiller. At the same time I had fatigue and nausea(more nausea when my headache would increase) I went to the urgent care and they checked for mono, low thyroid, pregnancy...etc etc. Didn't find anything and sent me home. A couple of days later I had chest pains and shortness of breath, and was feeling so fatigued I could barely get up the stairs from our basement. Back to the doctor and they checked my heart and did a chest xray, found nothing and sent me home. Fast forward about a month, I've had a clear lumbar puncture, clear MRI and have been sent to a neurologist, he discovers that my ANA is 1:1280 and sends me to a rheumatologist, the rheumatologist finds nothing after many more tests and sends me back to the neurologist. During this time of being passed back and forth more symptoms developed. I had numbness in my face, tongue and lips and all along my left side, my arm and leg had a cold sensation in them but weren't cold to the touch, muscle aches and cramps came and went, I started with a weird muscle twitch in my neck, I would get horrible stabbing in my chest where it would hurt to breathe in deep and than it would go away. My arms and legs feel weak and tire easily, my eyeballs are achey and hurt to look around, I've completely given up wearing my contact lenses. I have ringing in my ears and a black spot in my left side vision. My headache will NOT go away. The neurologist put me on Neurontin which is helped immensely with the numbness and tingling but I still have the fatigue, headache, ringing in ears, weakness, trouble thinking and remembering, chest pains and so many bladder infections. The neurologist said it would be good to go to Mayo Clinic in Minnesota as he doesn't know what to look for next, I have an appointment in one week exactly. I was wondering if anyone has any thoughts as to what I might expect when I get there. I guess I am going in to internal medicine and will be there a week getting different tests. I know that some people on here have expressed that Mayo ***** for MS diagnosis. At this point I feel like I probably have MS, I can't imagine what else it could be. The neurologist said that we couldn't rule it out yet....I hope I'm not going to the worst place in the country looking for an MS diagnosis! That's my story, just thought I'd share...not sure what is ahead for me. My mom (bless her heart) has been taking care of me and my family since Sept. Some days I am literally bedridden with pain and fatigue. She lives 7 hours from here so it is a big sacrifice for her, but I thank God for the help. Blessings to you all!