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QUESTION????

What is the difference between CIS and MS?
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494976 tn?1302710701
I am diagnosed with CIS. Yes it is true some people with CIS never progress to clinical MS. If you have lesions with CIS the chance of you developing clinical MS is far greater.
More people are being diagnosed  earlier, ie: CIS with the role of MRI.

Aimee.
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751951 tn?1406632863
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Avatar universal
Thanks, I've read CIS alot on this forum but was not sure exactly what it meant.  I guess maybe some people are dx'd with CIS before they get a confirmed dx of MS,  or can they never progess to MS?

Thanks,
lala
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146298 tn?1258712247
The term “clinically isolated syndrome” (CIS) has been used to describe a first neurologic episode that lasts at least 24 hours, and is caused by inflammation/demyelination in one or more sites in the central nervous system (CNS). The episode can be monofocal or multifocal:

    * Monofocal episode—The person experiences a single neurologic sign or symptom—for example, an attack of optic neuritis—that’s caused by a single lesion.
    * Multifocal episode—The person experiences more than one sign or symptom—for example, an attack of optic neuritis accompanied by weakness on one side—caused by lesions in more than one place.
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