Aa
Aa
A
A
A
Close
Avatar universal

Antiphospholipid Syndrome

Is  anyone else out there who has been diagnosed with Antiphospholipid Syndrome?
2 Responses
Sort by: Helpful Oldest Newest
566038 tn?1216543378
My wife was diagnosed with antiphospholipid syndrome 8-9 years ago. She suffers from memory loss, tia's, mini seizures, fatigue, numbness, changes in vision, confusion, depression, and more.

I'm up at 4:30 in the morning looking for any new information. Her condition is getting much worse with more frequent seizures where she will just "zone out." She has changed so much since I married her. At this point, I'm at a loss and have no idea what to do to make her better.
Helpful - 0
545944 tn?1227827002
SBF
Hi Lhr,
APS can be a very complex autoimmune condition, seen primarily in women (9-1), that's being studied along with Lupus and other autoimmune diseases.  Patients may manifest with diverse symptoms and should be tested for lupus anticoagulant (LAC) and anticardiolipin (aCL) antibodies.

Most patients have LAC and aCL immunoglobulin G (IgG) antibodies and the diagnosis requires the presence of clinical and biological features.  In recent studies the use of synthetically created peptides that focus on neutralizing the damaging anti-b2GPI antibodies may represent a possible therapeutic approach to treating APS.  

Neurologic or imaging studies should be performed based on the presence of Central Nervous System symptoms, usually involving a CT or MRI scan and daily treatment with low-dose aspirin may be considered appropriate if there are indications of clotting abnormalities or stroke.

Infectious agents are thought to trigger the autoantibody production but may also induce an inflammatory process that eventually favors clotting. The role of inflammation in APS could indicate environmental triggers or a genetic susceptibility, but is still unknown.
Helpful - 0
Have an Answer?

You are reading content posted in the Neurology Community

Top Neurology Answerers
620923 tn?1452915648
Allentown, PA
5265383 tn?1483808356
ON
1756321 tn?1547095325
Queensland, Australia
1780921 tn?1499301793
Queen Creek, AZ
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Find out how beta-blocker eye drops show promising results for acute migraine relief.
In this special Missouri Medicine report, doctors examine advances in diagnosis and treatment of this devastating and costly neurodegenerative disease.
Here are 12 simple – and fun! – ways to boost your brainpower.
Discover some of the causes of dizziness and how to treat it.
Discover the common causes of headaches and how to treat headache pain.
Two of the largest studies on Alzheimer’s have yielded new clues about the disease