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Systemic allergy and donor graft

I am a 54 yr old female wit LOTS of allergies - 4 months post op from ACL repair with dissolvable screws and a donor tendon.  3weeks ago I had sinus surgery. I had absolutely no problem with ACL surgery but sinus surgery I had allergic reactions to tapes, morphine in the hospital. Within two days i had hives and breathing problems so d/c the antibiotic, still continued having hives and breathing problems - allergist said it was a reaction to Prednisone.  We did a VERY fast taper on Prednisone (40 mg -4 days) the fifth day I ballooned particularly the face and knee.  A week later Went in for my maintenance dose allergy shot and had a systemic reaction to it immediately ( first time). Something has my body hyper reactive - so I am wondering if I could be reacting to the stuff that is in my knee? The knee stays a little bit swollen and two tender spots but not red nor itchy.  Grasping for straws.... My GP tested me for auto immune diseases but results neg.
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Update test for autoimmune disease was positive -ANA
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Hi!!

I am 35, from India, my blood group is B+, I am ready to donate my part of kidney, interested contact me ***@****
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If you were fine before your sinus surgery, I don't think it would be the graft in your knee.  All the cells are stripped out of grafts like that, so they're basically inert and your body won't react to them.  Almost sounds like you had a reaction to the pre-op antibiotics or the anesthesia.  
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