If the maternal age is advanced following are taken to be pointers towards chromosomal abnormality like Down's which is trisomy 21-- Sonographic markers include thickness of the nuchal fold, cardiac abnormalities, duodenal atresia, shortened femur, shortened humerus, renal pyelectasis, absence of the nasal bone , a hyperechogenic bowel, and a choroid plexus cyst. None of these markers are specific, and false-positive rates have been reported. Radiologist alone would not be able to make the decision, a multidisciplinary approach with involvement of a medical geneticist or a genetic counselor is required. Fetal echocardiography should also be performed.
does this mean that if the maternal age is not advanced (i.e. 25) these are not considered markers for chromosomal problems?
Thank you for your quick response, and in advance for your next one?
Advanced age is an important risk factor, still considering your findings risk for chrosomal abnormality is there, consultation with medical geneticist or a genetic counselor is required.