I have a 62 year old male friend who had histoplasmosis 40 years ago. He almost died but finally recovered. Doctors told him that he would have lesions on his lungs for the rest of his life. On May 10, 2019 he went for a low dose CT lung screening as part of a physical exam. He has smoked a little less than a pack of cigarettes a day for 42 years. The CT Impression was "Macro lobular mass right upper lobe 7.2 cm that s solid with punctate calcifications within it. Abuts anterior wall and is difficult to say if it involves wall or not. No involvement of underlying rib." He had multiple calcified nodules on left lung and one noncalcified on left lung. Apical scarring and thickening on both lungs. Is it possible that this large mass is a result of the histoplasmosis? They are making him an appt with a pulmonologist for evaluation and biopsy. He is very scared. His O2 saturation is 97% and he is asymptomatic at this time. Any response would be appreciated.