I was diagnosed with Jo-1-positive polymyositis several months ago. I am a 48YO female. My HRCT did not show overt ILD. It showed minimal volume loss at the base of both lungs, mucus plugs, and calcified granulomas scattered throughout both lungs. I am under the care of a pulmonologist, who performed another PFT yesterday. Here are my results, in part:
Fvc % Predicted: 116
Post Fev1/Fvc: 82
Fev1 % Predicted: 124
Fef 25-75% Pre Bronchodilator: 102
Fef 25-75% Post Bronchodilator: 125
My MVV was 66%.
I had an esophageal manometry test two days ago and am awaiting the official results. The RN who performed the test said I have weak pressures, causing swallowing difficulties. I had to swallow two or three times (rather than once) to get her bolus of water down each time. The pulmonologist said yesterday that must be the cause of my intermittent SOB -- the food being stuck in my esophagus puts pressure on my trachea. I had a sleep study recently that showed very mild OSA but was remarkable for hypoxemia (in the 80s) throughout the night, even when I was awake. The pulmonologist and neurologist believe my weak chest wall muscles cause this problem when I am lying down.
My official diagnosis from the pulmonologist is reactive airway disease. I am concerned I am losing function because of my neuromuscular disease. I take CellCept and prednisone for the polymyositis. Does anything about my PFT look significant? Why is my MVV so low? Can I do anything to improve my muscle tone? I have a young child and am concerned about long-term health issues.
Thank you very much for your help.