Aa
NSU diagnosis and Doxycycline
Well, I caught something on February 22nd of this year after receiving oral sex. I'm male by the way. I have tested TWICE for Chlamydia/Gonorrhea and came clean and one test for NGU which I came clean. I was first given Zithromax 1.5g over three days which helped the discomfort in my urethra. In addition to the irritable urethra, there was a strong burning sensation on the surface of the glans and part of my foreskin.
Due to this burning on the glans, I have been using Clotrimazole 1% cream for over three weeks now and it's slowly helping but it still gets irritated. The doc suspected a fungal infection. I did three days of (600mg/day)Cefdinir for the urethral "infection" even though he didn't test anything positive. I quit the Cefdinir because it wasn't gentle on my stomach, but mostly because I was being a wimp about it.
Well, now more than 6 weeks later, I went to a new doc (lost my insurance) and he did a "urinalysis" and said that I tested positive for NSU. I'm under the assumption that it's not "specific", but just based upon white blood cells in urine as well as a visual inspection, which it was red and itchy by the way. I DID NOT get to see results or any counts. Anyways, he prescribed me Doxycycline (200mg/day) for a week. I'm on the sixth day and the irritation AFTER urinating seems to be coming back. It's a fullness sensation that is very uncomfortable.
It has markedly IMPROVED over where it was a week ago, but it seems to be coming back the last two days. Here is the gist: How effective is Doxycycline on NSU and how soon should I be "cured"? I am I just worrying? Will a week of Doxycycline be enough to nip this NSU in the bud? Will Doxycycline continue to be effective after I finish my 14 pills in one week? Or perhaps, should I ask for another week of Doxycycline, which would be ok too since this drug is DIRT CHEAP and is absolutely wonderful in terms of side effects. The side effects are only mildly annoying, which cannot be said about other drugs I have sampled. However, I hate the "gut rot" as I call it...
Due to this burning on the glans, I have been using Clotrimazole 1% cream for over three weeks now and it's slowly helping but it still gets irritated. The doc suspected a fungal infection. I did three days of (600mg/day)Cefdinir for the urethral "infection" even though he didn't test anything positive. I quit the Cefdinir because it wasn't gentle on my stomach, but mostly because I was being a wimp about it.
Well, now more than 6 weeks later, I went to a new doc (lost my insurance) and he did a "urinalysis" and said that I tested positive for NSU. I'm under the assumption that it's not "specific", but just based upon white blood cells in urine as well as a visual inspection, which it was red and itchy by the way. I DID NOT get to see results or any counts. Anyways, he prescribed me Doxycycline (200mg/day) for a week. I'm on the sixth day and the irritation AFTER urinating seems to be coming back. It's a fullness sensation that is very uncomfortable.
It has markedly IMPROVED over where it was a week ago, but it seems to be coming back the last two days. Here is the gist: How effective is Doxycycline on NSU and how soon should I be "cured"? I am I just worrying? Will a week of Doxycycline be enough to nip this NSU in the bud? Will Doxycycline continue to be effective after I finish my 14 pills in one week? Or perhaps, should I ask for another week of Doxycycline, which would be ok too since this drug is DIRT CHEAP and is absolutely wonderful in terms of side effects. The side effects are only mildly annoying, which cannot be said about other drugs I have sampled. However, I hate the "gut rot" as I call it...
It could be 'Mycoplasma Genitalium' bacteria that is causing repeated irritation despite the Doxy. Its a form of STD which is now on the rise, and difficult to diagnose. It would normally show up as a case of NSU/NGU in that it is Non Chl / Non Gon in origin.
The problem with this one is that most places don't test for it directly and it can take months in a lab to culture it.
MG (as it is known) has practically the same symptoms as Non Specific infections like NSU/NGU however does not respond well to the treatments normally given for Non Specific infections. It is something to discuss with your specialist to try and rule this one out..
The problem with this one is that most places don't test for it directly and it can take months in a lab to culture it.
MG (as it is known) has practically the same symptoms as Non Specific infections like NSU/NGU however does not respond well to the treatments normally given for Non Specific infections. It is something to discuss with your specialist to try and rule this one out..
3 Comments
This is good info, but the threads you've been posting on are all quite old. This one is from 2009. I imagine that whatever he had going on is resolved by now.
I don't know if it's been approved everywhere, or where you live (and I don't need to know), but the US FDA has recently approved a new MG test - https://www.fda.gov/news-events/press-announcements/fda-permits-marketing-first-test-aid-diagnosis-sexually-transmitted-infection-known-mycoplasma Hopefully, it will eliminate some of the lingering issues for people.
I don't know if it's been approved everywhere, or where you live (and I don't need to know), but the US FDA has recently approved a new MG test - https://www.fda.gov/news-events/press-announcements/fda-permits-marketing-first-test-aid-diagnosis-sexually-transmitted-infection-known-mycoplasma Hopefully, it will eliminate some of the lingering issues for people.
Yeah, I know the post is quite old, but I think the response is still quite pertinent. When you search for this type of question on the internet, the O.Ps post comes up quite high in the search rankings, so a lot of people view it.. The issue with MG in the UK/EU is that it is not readily tested for over here. There arent standard tests available at the local GUM Clinic ( so walk-in/symptomatic patients won't initially be screened) - This is more a GUM Complex Clinic referral issue (Recurrent & Problematic infections that don't clear with standard AntiBiotics).
The alarming thing is, that it is not a well-known infection in the UK/EU, although quite prevalent if statistics are anything to go by.
More awareness initiatives are needed to inform people of the lesser-known STI's like MG... such as Tric, LGV, Molluscum....
The alarming thing is, that it is not a well-known infection in the UK/EU, although quite prevalent if statistics are anything to go by.
More awareness initiatives are needed to inform people of the lesser-known STI's like MG... such as Tric, LGV, Molluscum....
Oh there are GUM Complex Clinics - that's good to know.
It's not that well known in the US either, though in 2015, the CDC (our NHS) called it "an emerging issue".
Trich is really well known here. Molluscum is somewhat known - doctors know about it more than patients do.
LGV is a real issue, and appears to be more problematic in the UK than in North America - for now. https://www.news-medical.net/health/Lymphogranuloma-Venereum-Epidemiology.aspx
Your info is awesome, but we also have a lot of people who've recently posted who are currently dealing with issues that could benefit from it. :)
It's not that well known in the US either, though in 2015, the CDC (our NHS) called it "an emerging issue".
Trich is really well known here. Molluscum is somewhat known - doctors know about it more than patients do.
LGV is a real issue, and appears to be more problematic in the UK than in North America - for now. https://www.news-medical.net/health/Lymphogranuloma-Venereum-Epidemiology.aspx
Your info is awesome, but we also have a lot of people who've recently posted who are currently dealing with issues that could benefit from it. :)
Simple. Perhaps you get infected again from your partner.
Abstain any sex (intercourse) and then repeat the NSU test. if you cannot avoid to have sex please use condom (avoid oral sex without) and repeat the test.
Abstain any sex (intercourse) and then repeat the NSU test. if you cannot avoid to have sex please use condom (avoid oral sex without) and repeat the test.
hey brother
i going thru the same thing one oral sex encounter and month half pain for it.i did two bout of doxycycline one of cefixine and still i had this mild burning in my penis , everythere i read they proclaim doxycycline is standard treatment for chlamydia and ngu put for some metablic reason it does work FoR some? I.M AT MY WICK END OVER THIS SO PLEASE TELL ME MORE ABOUT THIS D-MANNOSE SUGAR AND HOW IT WORKS BECAUSE MAYBE YOU FOUND THE NEXT BEST CURE
i going thru the same thing one oral sex encounter and month half pain for it.i did two bout of doxycycline one of cefixine and still i had this mild burning in my penis , everythere i read they proclaim doxycycline is standard treatment for chlamydia and ngu put for some metablic reason it does work FoR some? I.M AT MY WICK END OVER THIS SO PLEASE TELL ME MORE ABOUT THIS D-MANNOSE SUGAR AND HOW IT WORKS BECAUSE MAYBE YOU FOUND THE NEXT BEST CURE
Well, things have become much more interesting and I even managed to somehow mangle my balls in the process, but they are ok.
The urethral pain IS subsiding which is bizarre. It's almost as if NOT using anti-biotics is helping me. And, either the "D-Mannose sugar supplement" helped me or it is just coincidence that I feel better. I quit all vitamins, cranberry juice and anything acidic...
I still do get a twinge after urinating sometimes but it's much better. The new strange symptom is now a "warm" urethra at night. Truely bizarre. And the anxiety about the whole situation does NOT help.
I also recented discovered that NGU generally "works itself out" within a period of about three months. However, present bacteria CAN still be theoretically spread, just like asymptomic STD's. In addition to that, some antibiotics such as Doxycycline don't always clear the bacteria. I found that stunning, especially in cases where Doxy failed UP TO 50% of the time in curing urethral bacteria infections(Mycoplasma, Ureaplasma, E Coli... etc.). Overall, anti-biotics are very effective.
Today, I went to a urologist and they found nothing in particular in my urine. I paid $120 bucks for that and talked to various doctors and nurses. What they suggested was a cystoscopy. That is inserting a camera on a tube to look at the inside of the urethra. I almost got sick to my stomach on that one but it was ok. $150 tops I figured... But more like $1050, and I don't even know if that includes the medication. No on that one for now. I'm going to get more D-Mannose. I'd I'll be friendly to my monkey in the process.
The urethral pain IS subsiding which is bizarre. It's almost as if NOT using anti-biotics is helping me. And, either the "D-Mannose sugar supplement" helped me or it is just coincidence that I feel better. I quit all vitamins, cranberry juice and anything acidic...
I still do get a twinge after urinating sometimes but it's much better. The new strange symptom is now a "warm" urethra at night. Truely bizarre. And the anxiety about the whole situation does NOT help.
I also recented discovered that NGU generally "works itself out" within a period of about three months. However, present bacteria CAN still be theoretically spread, just like asymptomic STD's. In addition to that, some antibiotics such as Doxycycline don't always clear the bacteria. I found that stunning, especially in cases where Doxy failed UP TO 50% of the time in curing urethral bacteria infections(Mycoplasma, Ureaplasma, E Coli... etc.). Overall, anti-biotics are very effective.
Today, I went to a urologist and they found nothing in particular in my urine. I paid $120 bucks for that and talked to various doctors and nurses. What they suggested was a cystoscopy. That is inserting a camera on a tube to look at the inside of the urethra. I almost got sick to my stomach on that one but it was ok. $150 tops I figured... But more like $1050, and I don't even know if that includes the medication. No on that one for now. I'm going to get more D-Mannose. I'd I'll be friendly to my monkey in the process.
COMMUNITY LEADER
LOL real sex. :(
Yes, that's what it means. There is still a bacteria in your urethra. If they haven't done a urine culture and sperm culture, they should. I still vote for a prostate exam, but I know you can't force your doc to do it.
Aj
Yes, that's what it means. There is still a bacteria in your urethra. If they haven't done a urine culture and sperm culture, they should. I still vote for a prostate exam, but I know you can't force your doc to do it.
Aj
I'm wondering since I have NSU/NGU, does that mean there are still "unidentified" bacteria in my urethra that may not be affected by the Doxycycline? I quit Doxy after 12 days worth two days ago and things are getting really touchy.
Because... some antibiotics affect certain bacteria but not others. I am wondering could a specific bacteria/irritation causing this discomfort be missed by the Doxycycline or just moderately affected by it given that Doxy DID seem to work for the first few days.
I'm suspecting the Urologist will swab for multiple types of bacteria along with violating my anus.
Because... some antibiotics affect certain bacteria but not others. I am wondering could a specific bacteria/irritation causing this discomfort be missed by the Doxycycline or just moderately affected by it given that Doxy DID seem to work for the first few days.
I'm suspecting the Urologist will swab for multiple types of bacteria along with violating my anus.
COMMUNITY LEADER
Well, I hope after all this, the urologist can offer some relief. I know it all stinks, though. Hang in there.
AJ
AJ
Well, the doc once again didn't suspect anything to do with Prostate given that I didn't have any of the other symptoms.
Doxycycline has lost it's effectiveness and I seem to have caught a "mystery disease" that causes urethral irritation. He told me to stop taking vitamin C and I did that a few days ago.
I have to wait all weekend for a Urologist and then spend even more money because I don't have insurance. Yay! For the time being, I'll just continue to suffer. Maybe I will just stop urinating all together. That means stopping drinking fluids. Only dry potato chips from now on.
Doxycycline has lost it's effectiveness and I seem to have caught a "mystery disease" that causes urethral irritation. He told me to stop taking vitamin C and I did that a few days ago.
I have to wait all weekend for a Urologist and then spend even more money because I don't have insurance. Yay! For the time being, I'll just continue to suffer. Maybe I will just stop urinating all together. That means stopping drinking fluids. Only dry potato chips from now on.
It could be something else as AJ had suggested.
Violate you??? They will have to do an exam, it's not violating you.
Violate you??? They will have to do an exam, it's not violating you.
Not sure what's going on, but the urethral irritation seems to be coming back. I can't believe it. The Doxycycline intially made it go away for the first 4 days and now it's coming back even though I'm still on Doxycycline. I'm at a complete loss. These past months have been real tough because of this. I wonder if I should try to get an appointment or tough it out with 5 more days of Doxy. Well the Doxy isn't tough, but the urethral symptoms are.
I tested clean for Chlamydia/Gonorrhea and NGU, but positive for NSU. What else could cause this and be related to a sexual encounter? I don't know where to look. Will they have to violate me with that lubed up finger?
I tested clean for Chlamydia/Gonorrhea and NGU, but positive for NSU. What else could cause this and be related to a sexual encounter? I don't know where to look. Will they have to violate me with that lubed up finger?
Well, the doc gave me another week of Doxycycline over the phone, which should completely wipe out the NSU given that it has been reduced greatly by a week of the said drug. I figured a few more days would cure it, but a week should be more than enough.
COMMUNITY LEADER
Try and talk to him on the phone first. No need to go back in and pay money unless he wants to do more testing.
Stranger things have happened than coincidences like timing for prostatitis. If you can't figure out another cause, have the prostate exam done.
Aj
Stranger things have happened than coincidences like timing for prostatitis. If you can't figure out another cause, have the prostate exam done.
Aj
I'm still not sure what the prostate would have to do with this, unless it conveniently started two days after receiving unprotected oral sex.
The symptoms are definitely better after 7 days, but it still feels like something is brewing and I might just need more Doxy. I'll have to talk to the doc again, and probably pay him money just to do that.
The symptoms are definitely better after 7 days, but it still feels like something is brewing and I might just need more Doxy. I'll have to talk to the doc again, and probably pay him money just to do that.
COMMUNITY LEADER
Doxy is very effective, and since the symptoms are returning, I'd follow up with your doctor and ask about a possible prostate exam.
Are you taking the meds twice a day or once? They should be taken twice a day.
AJ
Are you taking the meds twice a day or once? They should be taken twice a day.
AJ
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