Aa
Confused-So much going on Do I take the Synthyroid
Hi
Where to begin. New blood results and so many things are too weird. Know I have Hashi but apparently now a bunch of other things going on. Help. She agreed to Synthroid 12.5 mg. Just don't know if I should start it with all these other things going on.
6/5/14
TSH 2.73 (.55-4.78)
FT3 2.9 (2.3-4.2)
FT4 1.35 (.89-1.76)
Reverse T3 24 (9.2-24.1)
TBOab 982.40 (24 (5.4-24.0) Did not supplement Was 10.4 in Dec.
Vit B12 800 (211-911) Did not supplement Was 417 in Dec.
Homocysteine 16.86 (3.7-13.9)
She said I had "Folate Trapping or something like that. So my body could not use the vitamins effectly.
I tested positive for that MTHFR gene (did it withou my knowledge) but so far hasn't told me exactly what do about it. But the Methylmalonic Acd is about mid-range, which is related.
Cholestesterol went up 56 pts in 4 months, no diet or lifestyle change. Agreed to go on Crestor. Within 2 days, had side effects that was advised to stop.
Vit D3 16 (30-100) Again did not supplement. This is wants 50,000 per week for 8 weeks. Guess that's safe. And I do not go out much do my legs, feeling like jello alot and dizziness.
Other confusing results
Low glucose
Slighly low Globulin
Slighly high Total Protein.
She also my Salvia Cortisol test was off but those results haven't made it into my portal yet.
So my basic question is do I start the Synthyroid or do I get these other issues under control before I try?
Especially since my FT4 is up there but so is my Reverse T3. Would a T4 only med just make more T4 and Reverse T3 Instead of T3?
Know it's a lot here but some it just doesn't make sense.
Thanks so much for any help.
Where to begin. New blood results and so many things are too weird. Know I have Hashi but apparently now a bunch of other things going on. Help. She agreed to Synthroid 12.5 mg. Just don't know if I should start it with all these other things going on.
6/5/14
TSH 2.73 (.55-4.78)
FT3 2.9 (2.3-4.2)
FT4 1.35 (.89-1.76)
Reverse T3 24 (9.2-24.1)
TBOab 982.40 (24 (5.4-24.0) Did not supplement Was 10.4 in Dec.
Vit B12 800 (211-911) Did not supplement Was 417 in Dec.
Homocysteine 16.86 (3.7-13.9)
She said I had "Folate Trapping or something like that. So my body could not use the vitamins effectly.
I tested positive for that MTHFR gene (did it withou my knowledge) but so far hasn't told me exactly what do about it. But the Methylmalonic Acd is about mid-range, which is related.
Cholestesterol went up 56 pts in 4 months, no diet or lifestyle change. Agreed to go on Crestor. Within 2 days, had side effects that was advised to stop.
Vit D3 16 (30-100) Again did not supplement. This is wants 50,000 per week for 8 weeks. Guess that's safe. And I do not go out much do my legs, feeling like jello alot and dizziness.
Other confusing results
Low glucose
Slighly low Globulin
Slighly high Total Protein.
She also my Salvia Cortisol test was off but those results haven't made it into my portal yet.
So my basic question is do I start the Synthyroid or do I get these other issues under control before I try?
Especially since my FT4 is up there but so is my Reverse T3. Would a T4 only med just make more T4 and Reverse T3 Instead of T3?
Know it's a lot here but some it just doesn't make sense.
Thanks so much for any help.
Cortisol is the stress hormone and stress not only affects the immune system but is shown to increase RT3 levels. I have also read the MTHFR may raise copper levels (and therefore zinc levels lower) which could affect RT3 as well.
"You can find yourself with high folate or high B12. i.e. your body will have problems converting inactive forms of folate and B12 to the active forms. So the inactive folate or B12 will simply build up in your serum, also inhibiting the active forms. Most serum folate tests are actually measuring folic acid, which needed to be converted to methylfolate to be used metabolically." -- MTHFR genetic defect – what it is and how it can affect you
"You can find yourself with high folate or high B12. i.e. your body will have problems converting inactive forms of folate and B12 to the active forms. So the inactive folate or B12 will simply build up in your serum, also inhibiting the active forms. Most serum folate tests are actually measuring folic acid, which needed to be converted to methylfolate to be used metabolically." -- MTHFR genetic defect – what it is and how it can affect you
It messed up in the post so I hope you understood.
My folic acid was >24
My B12 is 800, isn't that sufficent.
So because of this mutant gene,( I have 2 copies so apparently I got it from both my parent-neither has this issue) it looks like all is well with the b12 but I'm not using it effectly?
Does this affect the thyroid in any way?
Like the raise in antibodies?
Or FT4 and reverse t3 being so high? Was 18 in Dec.
That's what confuses me, she agreed to Synthyroid but will it just raise the FT4 and Reverse T3 instead of going to the F3 where it's needed?
My folic acid was >24
My B12 is 800, isn't that sufficent.
So because of this mutant gene,( I have 2 copies so apparently I got it from both my parent-neither has this issue) it looks like all is well with the b12 but I'm not using it effectly?
Does this affect the thyroid in any way?
Like the raise in antibodies?
Or FT4 and reverse t3 being so high? Was 18 in Dec.
That's what confuses me, she agreed to Synthyroid but will it just raise the FT4 and Reverse T3 instead of going to the F3 where it's needed?
TPO antibody levels correlate with the active phase of autoimmune thyroid disease. When I corrected my B12 deficiency my homocysteine was somewhere in the 6 range. So when it started to rise again to the 8 range I knew something was up. I had other B deficiency states of course! but I figured that out from the crack down the middle of my tongue showing up again.
Excerpts from Life Extension - Is Homocysteine Making You Sick? - A New Bioactive Form of Folic Acid Can Lower Stubbornly High Homocysteine Levels When Ordinary B-Vitamins Fail...
"The Life Extension Foundation® and other experts believe that this upper limit of normal is far too high for optimal health. Studies indicate that people with homocysteine values greater than 8.5 µmol/L are at increased risk of atherosclerosis,heart attack,and stroke."
"The MTHFR C677T gene variant is the single most important genetic determinant of blood homocysteine values in the general population."
"For this affected group, taking the bioactive folate supplement, 5-MTHF, may be just what the doctor ordered—a clinically tested and superior alternative to regular folic acid. 5-MTHF is seven times more bioavailable can cross the blood-brain-barrier, and is unlikely to mask a vitamin B12 deficiency as folic acid can do. For the first time, those who carry this gene variant can safely reduce their risk of homocysteine-related health problems using an inexpensive, non-prescription folate supplement.
One way of finding out if you carry this gene variant is if your homocysteine level remains stubbornly elevated despite taking high doses of folic acid, vitamin B12, and vitamin B6."
Excerpts from Life Extension - Is Homocysteine Making You Sick? - A New Bioactive Form of Folic Acid Can Lower Stubbornly High Homocysteine Levels When Ordinary B-Vitamins Fail...
"The Life Extension Foundation® and other experts believe that this upper limit of normal is far too high for optimal health. Studies indicate that people with homocysteine values greater than 8.5 µmol/L are at increased risk of atherosclerosis,heart attack,and stroke."
"The MTHFR C677T gene variant is the single most important genetic determinant of blood homocysteine values in the general population."
"For this affected group, taking the bioactive folate supplement, 5-MTHF, may be just what the doctor ordered—a clinically tested and superior alternative to regular folic acid. 5-MTHF is seven times more bioavailable can cross the blood-brain-barrier, and is unlikely to mask a vitamin B12 deficiency as folic acid can do. For the first time, those who carry this gene variant can safely reduce their risk of homocysteine-related health problems using an inexpensive, non-prescription folate supplement.
One way of finding out if you carry this gene variant is if your homocysteine level remains stubbornly elevated despite taking high doses of folic acid, vitamin B12, and vitamin B6."
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