cytomel suppressing tsh

[summerskye2002]

I need good information about how cytomel suppresses tsh to show new doctor...any ideas where to get this?

[summerskye2002]

showed to doctor did not phase him still stuck on tsh level even though free t3 and free t4 are in perfect range and I am in perfect health. I need help. All my doc's are stuck on stupid. I am seeing yet another new one on the 31st and I need something super convincing as I do not need my meds messed with. I do not want to be a lump of cold goo.

[gimel]

TSH can be suppressed by either Free T3 or Free T4 levels.  It is a normal occurrence when taking significant doses of thyroid med, adequate to relieve symptoms.   Following is a link to one scientific study on the subject.  Note the statement that, "When TSH was suppressed, FT4 was elevated in 30.4% but normal in 69.6% of patients."

http://www.ncbi.nlm.nih.gov/pubmed/1366242

In addition there are scientific studies that have concluded that biochemical tests for thyroid function are not very useful in trying to determine the euthyroid state for a hypo patient.  For that reason clinical treatment for symptoms is the most effective way to treat hypo patients.

That is why I always say that a good thyroid doctor will treat a hypo patient clinically by testing and adjusting Free T3 and Free T4 as necessary to relieve symptoms, without being constrained by resultant TSH levels.  You can get some good insight into clinical treatment from this letter written by a good thyroid doctor for patients that he sometimes consults with after initial tests and evaluation.  The letter is then sent to the participating doctor of the patient to help guide treatment.  In the letter, please note the statement, "the ultimate criterion for dose adjustment must always be the clinical response of the patient."

http://hormonerestoration.com/files/ThyroidPMD.pdf

[capewind]

wow great, thanks
will check out " Pulse Online by Dr Toft, ex President of the British thyroid association"

[jacrjacr]

I was told by one doctor that when you are taking t3 with t4, the tsh will always be suppressed to they pay close attention to the ft3 and ft4 instead. That being said...
I don't know if the following is helpful but you can email Louise.***@**** and ask for a copy of the following article in Pulse Online by Dr Toft, ex President of the British thyroid association, of which this is an excerpt:-

6 What is the correct dose of thyroxine and is there any rationale for adding in tri-iodothyronine?

The appropriate dose of levothyroxine is that which restores euthyroidism and serum TSH to the lower part of the reference range – 0.2-0.5mU/l.

In this case, free thyroxine is likely to be in the upper part of its reference range or even slightly elevated – 18-22pmol/l. Most patients will feel well in that circumstance.

But some need a higher dose of levothyroxine to suppress serum TSH and then the serum-free T4 concentration will be elevated at around 24-28pmol/l.

This ‘exogenous subclinical hyperthyroidism’ is not dangerous as long as serum T3 is unequivocally normal – that is, serum total around T3 1.7nmol/l (reference range 1.0-2.2nmol/l).

Even while taking the slightly higher dose of levothyroxine a handful of patients continue to complain that a sense of wellbeing has not been restored. A trial of levothyroxine and tri-iodothyronine is not unreasonable. The dose of levothyroxine should be reduced by 50µg daily and tri iodothyronine in a dose of 10µg (half a tablet) daily added.

****

This is a link re osteoporosis and their are lots of interesting topics at the top of the page.

web.archive.org/web/2010112...

[capewind]

I though it helped you obsorb the T4, TSH?  :-/
I think by prescription only.