I don't know but many others may and post .... we are here for you and WELCOME to the COMMUNITY .. hang in there ...
I don't know anything about Thyroglobulin yet, but I'm sure someone on here will. Hang in there.
What method they use to determine the Tg AB concentration? From what I have read some methods [sandwich method] is not reliable.
Those tests mean different things for different people.
If you are a thyroid cancer survivor, they mean one thing.
If you are a thyroid patient in the process of looking for a diagnosis and treatment, they mean something else altogether.
You have a goiter, and are trying to get treatment, yes?
If that is the case, then it means you have thyroglobulin, which you need to produce thyroid hormones, and you have thyroglobulin antibodies, at a very low level.
As 898 points out, the TGab test you had may or may not be acurate, and the TGab test results are very low, meaning they will not likely give you a lot of trouble.
But, it is a positive test for antibodies. The antibody titer may fall over the next year, and test negative at a later date. The antibody titer may climb, and start to harm your thyroid one day.
If the TGab goes high enough, it will start to affect your Thyroglobulin, and you will make fewer hormones.
Right now, today, the test results are a little disapointing, but not a major problem.
If you are a cancer survivor, then TGab at any level is bad, because it will mess up the Thyroglobulin test. Thyroglobulin is produced by any thyroid cell, whether it is healthy or cancerous. When doctors are screening cancer patients for risidual undetected cancer after a total thyroidectomy, they run a thyroglobulin test and hope to see as small a result number as possible. I don't remember the number they look for, but it is very low, like 1.0 or less. If there is TGab present, it makes the TG test result suspect, and it is assumed the test is not trustworthy.
I apologize if any of the last paragraph is inacurate or upsets anyone. I am not well versed on thyroid cancer, and do not mean to give out bad information.
Actually AR-10 has been hanging around us cancer patients too long. He's right on the money for thyroid cancer.
Thyroglobulin (Tg) *is* the cancer marker (for papillary and follicular) and, if you didn't have Tg antibodies, having your Tg level that high would indicate recurrence after treatment. *HOWEVER* - having the antibodies makes the Tg test so unreliable that it's unusable for the marker.
However, *If* you were a thyroid cancer patient and your Tg was that high - regardless of antibodies - they would order RAI just to see if there was a recurrence.
And keep in mind if you have thyroid cancer and any thyroid tissue is left in place i.e., a partial, then you cannot use this test at all for a marker. I asked my Endo this at my last visit .. I had a partial so there is most likely thyro being produced.
Hi everyone,I just had an ultrasound test on my thyroid nodule and showed it to be 0.9 cm bigger than 2 years ago(2.1cm in 2005). I also had blood work done and my hormone are fine but the Thyroglobulin is 109, there are no antibodies. I am cheduled for FNB this Thursday. Does anyone know what that number 109 can mean?
Does this mean I have Hashis!?
Hope you are feeling better today!
You would need to have your complete thyroid antibodies run to determine whether or not you have Hashi's. The TgAB is only an antibody for thyroglobulin.
Hope you find the answer soon, hang in there.!!