Hashimotos Thyroiditis and low APL levels

[sandrad77]

I suspect I have Hashimotos as it was suggested a few years ago. I just had blood work done and my Alkaline phosphatase (ALP) was 2 points below normal. My muscles and joints ache constantly as well as being extremely fatigued. I generally exercise 4 to 5 days a week and run 20 miles a week. This stopped me in my tracks. Has anyone with Hashimotos experienced low Alkaline Phosphatase? My friend who is a PA suggested that it could be caused due to my thyroid. My TSH is still WNL but has been climbing in the last 3 tests over a year. My dr has not checked t3, t4 or for antibodies. I'm going to talk to him tomorrow and demand more thyroid tests. I want to make sure I have my facts straight. TY ❤

[Red_Star]

"Low alkaline phosphatase levels have been connected to hypothyroidism, Hashimoto’s, and some other autoimmune conditions as well. It’s a good indicator of a poorly functioning gut. But what’s causing it is not always straightforward. One of the things alkaline phosphatase does in the body is it helps us neutralize lipopolysaccharides, which are inflammatory toxins from our gut bacteria; our dysbiotic gut bacteria. One of the things to do is increase probiotics.

Another thing is, alkaline phosphatase tends to get depleted in an acidic environment. So, doing magnesium glycinate at bedtime can be very, very helpful in rebalancing our body’s acidity. That’s something that I would also recommend. Also, potentially increasing zinc to 30mg a day and optimizing vitamin D levels. Generally, with people who get into remission, I will see their Vitamin D levels between 60 and 80."

- Dr. Izabella Wentz

[sandrad77]

Thank you Dr Wentz. I have been taking 1 VSL3 capsule for a few years every morning. I also take 200mg of magnesium citrate blend at bed. I will try the other that you recommended. Since my APL is low, should I consider a rheumatologist ?

[Red_Star]

I'm not a doctor. I found that comment from Dr Wentz. My rheumatologist was excellent..he ordered a full work up.  You might consider seeing a rheumatologist as well as an endocrinologist.

[sharanbr]

I have severe body/joint aches. My doctor did a lot of tests to find out the cause of body aches (including B12, Vit D, CRP, CPK, Ferritin, Sugar, minerals etc.) but did not order ALP test.
Let me know how it goes for you because body/joint pain is really coming in the way of my day to day life

[sandrad77]

I will. Did they find any deficiencies for you?

[gimel]

I have no information to offer on the APL being affected by hypothyroidism.  I do want to suggest that you insist on being tested for both Free T4 and Free T3, cortisol,  Vitamin D, B12 and ferritin.   Free T4 andFree T3 (not Total T4 andTotal T3)  are the biologically active thyroid hormones you need to know about.   The other tests are for important variables that affect thyroid hormone metabolism.   TSH is useful in diagnosis only when at extreme levels.   The most important diagnostic is symptoms. So I suggest that you click on this link and check the boxes of any symptoms you have and it will give you a total score to compare to the ratings below.  You can make a copy and give it to the doctor.

http://www.thyroid-australia.com/lowthyroid.htm

If you wan some written info to use with the doctor, click on my name and then scroll down to my Journal and read the one page overview of a paper on Diagnosis and Treatment of Hypothyroidism: a Patient's Perspective.  

[sandrad77]

This is very helpful. Thank you.