The T4 part of your med has a half life of about a week. So missing 2 days would not have a huge effect. On the other hand T3 has a half life of less than a day, so serum levels changes fairly quickly. It might not make much difference, but I suggest waiting until you have taken your med for another day or two just to be sure your test results are not significantly affected. Also, be aware that on the day of the blood draw you should not take your daily thyroid med until after the blood draw for thyroid related tests, in order to avoid false high results. This is even recommended in the ATA/AACE Guidelines for Hypothyroidism.