I have been dealing with extreme fatigue and now aches and pains on my knees and low back. Had seen a Rhuemy in 2010, and was put on plaquenil for " connective tissue disorder" for about a year. Helped with hair thinning and other symptoms. Since then, moved and took new job. Symptoms have emerged along with new positive tests- HLA-B27 positive ,Cyclic Citrullinated Peptide Antibody- positive, Creatine Kinase, 147 (high end of normal) and Ferritin very low 8. No word from the Dr. or nurse except for my 6 week follow up. Aches and pains are getting worse along with fatigue... any advice?