What could be causing my autoimmune like symptoms?

[meganlaney10]

I've been dealing with dizziness for about 10 years now but it used to be pretty sporadic so I wasn't too worried about it. About three years ago it became very common and I passed out a couple of times. I had a positive tilt table test and was diagnosed with vasovagal syncope. But around the same time the dizziness started getting worse I started having other symptoms. I have 'brain fog'/confusion, headaches, periods of absolutely exhaustion/weakness where I can't even get out of bed, internally feel like I'm on fire at the same periods of the exhaustion, knee/joint pain during those periods. These periods of extreme symptoms come and go. Except I have no energy pretty much all the time. I also get frequent reflux and have IBS. I'm 35, female. I've had a brain MRI that came back abnormal showing lesions, but neurologists said they are tiny and it's not MS. I had a positive QSART test (reduced sweat output) but the rest of the autonomic testing passed so they don't believe it's autonomic related. My latest MRI showed mucosal thickening around my maxillary sinuses, flow-voids visualized in major vessels of anterior and posterior circulation, soft tissue prominence in the nasopharynx. Blood tests have shown inflammation and high C Reactive Protein. I've also had a sleep study and been diagnosed with PLMD (periodic limb movement disorder). It seems like I keep getting all of these small puzzle pieces but nobody can put it together to figure out what the underlying cause is. I've been bouncing around for years and am just looking for an answer now... Has anyone been through similar? Any ideas?

[Jls34]

Non celiac gluten sensitivity. Over 300 possible symptoms can be associated. Only cure is gluten free diet!

[Paxiled]

Had a thorough thyroid test, not just testing for tsh but for T3 and T4?  Been tested for B12 deficiency?  Been tested for chronic fatigue syndrome or fibromyalgia?  Lyme disease?  When you have the kinds of things you're describing, you get into the very hard to diagnose stuff that are more diagnosed by symptoms than tests but perhaps it's time to go somewhere where they have better docs, like the Mayo Clinic.  

[meganlaney10]

Thanks for the response! T3, T4 and TSH are all normal. I haven't been tested for B12 deficiency yet, so I'll ask for that. I have been tested for Lupus, Lyme, RA - all negative. I've thought about trying to get into the Mayo Clinic, but at this point I'm not even sure what type of doctor to request an appointment with there!

[Paxiled]

I'm no expert, but I think that's the point, I think they work in teams and will tell you who you need to see.  That at least is my understanding and why they are better at it than others are.

[meganlaney10]

Ah okay, that's good to know. Thank you!