I am a 46-yr. old female with type 2 bipolar disorder. I have been taking 750 mg of Lithium (Eskalith and Lithobid)for 6 years. I also take 200 mg of Lamictal. The medication controls my illness extremely well (after a few adjustments) and I am doing great. I am in good health otherwise with the exception of acid reflux. However, I do have polyuria. My doctors, who are excellent, check my lithium levels regularly and they are always good. They don't seem concerned about the polyuria. However, although I have gotten used to it is very inconvenient and embarrassing, particularly since I don't like discussing what causes the polyuria. When I drink soda, which is often, I have to go to the bathroom at least 10-12 times a day, sometimes more. I intend to cut back on the soda but even if I do I still have the polyuria. I am worried about the long-term effects of the polyuria on my kidneys. I am frightened about renal failure or diabetes. I really don't want to stop the lithium since that would likely cause a serious problem with my bipolar disorder. Is there anything I can do and should I be concerned? Thanks.