I think your NAC should be taken apart from food -- amino acids generally do better that way. The rest are fine with a meal. Be careful with zinc -- make. sure you don't supplement with too much, it's toxic in high doses. Now, as for the specific question of whether these should be taken with your health problem or whether they're going to do you any good or not if you're trying to treat it, you'll probably need to seek professional guidance -- that's a pretty specific problem. Doctors probably won't know anything about using natural medicine for anything, unless you find one who practices integrated medicine -- if you do that would be a great person to ask. A naturopath might know, might not. As this is at least in part a hormonal problem, I'm not sure where you're going with these supplements, but I'm guessing you have looked in to it. But if you don't know if they're okay with this problem, you haven't looked into it well enough yet so again, make an appointment with someone who knows both the nature of your problem and the nature of natural medicine. Good luck.