Hello~I am so sorry that you grandfather is having these issues.
I would definitely try the Milk Thistle, I would use the tincture instead of capsules as it gets into the system faster. Other herbs to try are: turmeric, dandelion root, resveratrol, and green tea.
If there is a naturopathic physician in your area, I would also see him/her, they have other ideas as well such as a liver detox program which helps lots of folks.