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Bendectin usage and infertility in female offspring

In the late 70s I was prescribed Bendectin - an anti-nausea drug, taken during my first trimester in two pregnancies. Both of my daughters,now in their early 30s appear to be sterile with no diagnosed foundations. The only thing I can think of is this drug that was taken off the market in the 80s.  Anyone else out there with a similar thought?
Regards
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Avatar universal
My mother took this drug while pregnant with me and my brother.  She did not take the drug while pregnant with my older sister.  We have no family history of infertility.  My sister has 4 children with no complications in her pregnancies nor any miscarriages.  Both me and my brother are completely Sterile. I have done 3 years of infertility treatments with no luck and has done the same with his wife.  My doctor doesn't really have an answer as to why I cannot get pregnant and has labeled me with PCOS even though I do not fit the symptom profile.   I believe this drug is the cause of my infertility and should be banned permanently.
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I took this drug in 1980.i was only 16 yrs old when i had my daughter.she didnt talk until she was 5yrs old.she didnt potty until she was 5yrs old either.sivehe has never been normal.she is also sterile.from age 7 shes been in and out of mental hospitals.it has been so hard taking care of her.Ihave had three more kids after her.they have their own kids now.no problems.i have six sisters,all have kids.no problems either.i was the only one to ever take this drug in my family.i know in my heart this drug damaged my daughter.i just wish i would have known then what i know now about this drug.i would have never taken it.my daughter is getting worse the older she gets.it really took a toll on me and my other three kids.
Why did you take the drug at 16?   I'm sorry to hear she has difficulties.  So, how old is she now then? 31 years?  Birth defects with the med are semi disputed. It seems like the birth defects were things like losing a limb, a finger, etc.  But you know what you know and if you think it is due to the medication, you could be right. There was a big class action suit against the maker years ago.  The pulled the drug not because any studies ever proved danger but because their insurance policy could not cover the disputes popping up.  Here's an interesting article. https://www.nytimes.com/1983/06/19/weekinreview/shadow-of-doubt-wipes-out-bendectin.html  But none of that matters as you care for your daughter.  Is she able to live on her own and have a normal life or does she still require your care?
Avatar universal
I have been thinking that Bendectin also caused reproductive issues with my daughter, as well as my son!!  My daughter has managed to get pregnant 3 or 4 times, but has had a variety of issues causing her to lose all but one child that she calls her "miracle child."  

But my son has also had similar issues and one partner miscarried shortly after conception, then his wife managed to carry one child to birth, but he was born with a very rare brain tumor due to a gene deletion.  He died shortly before his 2nd birthday.  

My son and his wife went to a well-known geneticist who is a specialist doing research into the very rare condition, but she couldn't explain why they had borne a child with this condition based on their genetics.  It was just a fluke.  

Taken alone, if either of these situations had occurred alone, I might have thought it was just a coincidence, but I've been thinking that the only medication I took during both pregnancies was Bendectin.  I even insisted on having natural childbirth because I didn't want to expose my babies to any type of drugs, but my nausea and vomiting became so extreme, my doctor suggested I take the Bendectin.  Everyone seemed to think it was safe, so I did accept the drug to help me keep food down.  

I've wondered for years if that caused reproductive problems with both of my kids.  They are extremely healthy and have high IQs, so they have no other issues that I know about.  I just found it very odd that in a family of very fertile people both of my kids have had issues reproducing.  That just seems suspicious to me.
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Avatar universal
I was given the drug Bendectine in 1973, 1976 and 1980.  Both my daughters have fertility issues.  My doctor for the 1980 (son) pregnancy hesitated giving me the drug because of results that showed some daughters of mothers that took the drug had fertility problems.  Sure enough  my daughters have the same exact problem and one actually had to go to a fertility clinic with the final success of triplets after 14 years.  My second daughter is taking the drug Clomid.  She has a daughter and is trying to get pregnant again but with difficulty.
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1194973 tn?1385503904
There is actually another post like this that dates back to 08 I believe. It might have info for you if you wish to read the posted comments.

http://www.medhelp.org/posts/Maternal--Child/anti-nausea-drug-banned-in-80s/show/158730
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