Aa
What is plan B
What is plan B if someone relapses after extended tx?
Im not SVR24 yet. Im still 5 months post TX and will have my final lab draw in Oct. I am SVR12 right now which puts me at a 99.7% chance of cure.
But your right, when one relapses, it usually happens shortly after EOT so my chances look pretty good.
Hope my fellow G3 ers are doing alright!
But your right, when one relapses, it usually happens shortly after EOT so my chances look pretty good.
Hope my fellow G3 ers are doing alright!
Once you get to SVR like you have done, aren't your chances of staying SVR real good?
Isn't the relapse most likely to happen soon after EOT?
Isn't the relapse most likely to happen soon after EOT?
I know, it really concerns me, I keep going back and forth. As to what I might do, I still have such brain fog at times, I have to remove my self from that thought process. And focus on EOT.
There are so many things I cant grasp, I have always thought my CBC staying solid was a good thing, and yet more and more I hear becoming anemic is a good sign of possible SVR. I know there are charts and graphs and papers but so much of the time they seem to stand in opposition of one another, so at this point some personal reality would be nice...IE; Has anybody had an experience in that there CBC stay within the normal range for 32 weeks of tx with peg./ copeg. and what was the outcome.
There are so many things I cant grasp, I have always thought my CBC staying solid was a good thing, and yet more and more I hear becoming anemic is a good sign of possible SVR. I know there are charts and graphs and papers but so much of the time they seem to stand in opposition of one another, so at this point some personal reality would be nice...IE; Has anybody had an experience in that there CBC stay within the normal range for 32 weeks of tx with peg./ copeg. and what was the outcome.
If I relapse I will try the sofosbuvir/riba combo OR try and get into a trial if there is one to get into. Sofosbuvir/riba hasnt shown that great of results for us G3's
Next year Gilead's treatment (sofosbuvir + ribavirin) for genotypes 2/3 is expected to be on the market in the US and later in Europe.
-----------------------------------------------------------------------------------------
On April 8, Gilead submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for sofosbuvir for the treatment of HCV infection. The data submitted in the NDA support the use of sofosbuvir and RBV as an all-oral therapy for patients with genotype 2 and 3 HCV infection. The Food and Drug Administration has set a target review date of Dec. 8.
Gilead plans to file for regulatory approval of sofosbuvir in other geographies, including the European Union, in the second quarter of 2013. The European Medicines Agency (EMA) has accepted Gilead’s request for accelerated assessment for sofosbuvir, a designation that is granted to new medicines of major public health interest. Accelerated assessment could shorten the EMA’s review time of sofosbuvir by two months. Granting of accelerated assessment does not guarantee a positive opinion from the CHMP or approval by the European Commission.
-----------------------------------------------------------------------------------------
On April 8, Gilead submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for sofosbuvir for the treatment of HCV infection. The data submitted in the NDA support the use of sofosbuvir and RBV as an all-oral therapy for patients with genotype 2 and 3 HCV infection. The Food and Drug Administration has set a target review date of Dec. 8.
Gilead plans to file for regulatory approval of sofosbuvir in other geographies, including the European Union, in the second quarter of 2013. The European Medicines Agency (EMA) has accepted Gilead’s request for accelerated assessment for sofosbuvir, a designation that is granted to new medicines of major public health interest. Accelerated assessment could shorten the EMA’s review time of sofosbuvir by two months. Granting of accelerated assessment does not guarantee a positive opinion from the CHMP or approval by the European Commission.
Thank you.
I imagine that we will buy some time by treating now. That tx you mentioned has about the same odds as the present one. Bocevergal (spelling?) mentioned another tx in the pipeline this morning but it wasn't clear to me if it applied to G3's. I wonder what relapse looks like. Does the previous VL come roaring back quickly? My Hep Doctor gives me a 40% chance of relapsing and says not to get my hopes up for a new cure anytime soon.
nuhepper
I imagine that we will buy some time by treating now. That tx you mentioned has about the same odds as the present one. Bocevergal (spelling?) mentioned another tx in the pipeline this morning but it wasn't clear to me if it applied to G3's. I wonder what relapse looks like. Does the previous VL come roaring back quickly? My Hep Doctor gives me a 40% chance of relapsing and says not to get my hopes up for a new cure anytime soon.
nuhepper
I spoke with my Hep C specialist Friday about this. If I do relapse, plan B will be to treat with sofosbivir and ribavirin for 16 weeks, this will be available for G3's who have relapsed in a couple months. Of course he is optimistic about SVR....he is my Dr.
I also asked about EOT ribavirin saturation, seems the test for that is not available here, but again he was very upbeat, he pointed out that my CBC has held solid through out tx.
I also asked about EOT ribavirin saturation, seems the test for that is not available here, but again he was very upbeat, he pointed out that my CBC has held solid through out tx.
You must join this user group in order to participate in this discussion.
You are reading content posted in the Hep C Gt3 Group
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.
