AFP L3% Marker - Total AFP High than Normal

[Brohim_2122]

My AFP tumor Marker test has always been less than 6.1 (normal upper limit) with the last one on 9/17/2020  5.7 . Another doctor recommended the triple biomarker  - DCP/AFP & AFP L3 and the result came back on 1/13/2021 with Total AFP of 7.1  (normal range 1.6 - 4.5 ng/ml). DCP < 1.0  and AFP L3 not detected. Should this be a concern?

My GI has scheduled an MRI. Last US was normal back in 6/24/2020 and my AST/ALT 20/22  on 12/31/2020 - always in the normal range since 2012.

I have been on Tenofovir for 2 1/2 years starting 4/1/2018. My last fibroscan was 4.4 kpa back in 2017 and I plan to do another fibroscan this month. Platelet level has been trending down for a while since starting Tenefovir but doctor doesn't appear concerned. CT back in 2019 was also normal.

Hbsag
9/17/2020 - 2211
1/8/2020 - 2734
4/15/2019 - 3188
7/31/2018 - 2608
2/9/2018 - 2772

12/31/2020
INR - 1  
PT - 10.9
Vit D- 58

Please advise.

Thank you.
    

[FingHb]

I would wait for your dr to advise you.  You can try Hbconnect.com and see if anybody can help there

[Brohim_2122]

Here is the latest MRI result  - 1/121/2021 . I will soon go the Fibroscan.

Thorax: Visualized thorax clear of significant pathology.
Liver: 8 mm T2 hyperintense, T1 hypointense, nonenhancing cyst and segment 7. No
enhancing mass. No biliary dilation..
Gallbladder: No stones or inflammation. Nondistended. This a linear T2 hypointense
structure extending along the anterior wall of the gallbladder from the neck to the
fundus, greatest in thickness at the fundus where it measures approximately 6-7 mm.
This is hyperintense on the Eovist sequences such as series 9, most conspicuous on
image 50.
Spleen: Unremarkable.
Pancreas: Unremarkable.
Adrenal Glands: Unremarkable.
Kidneys: No acute pathology. 1.9 cm simple cyst upper pole left kidney, enlarged from
prior..
Stomach: Unremarkable.
Bowel: No obstruction, inflammation, or mass.
Vasculature: No significant pathology.
Lymph Nodes: No pathologically enlarged or abnormal nodes.
Abdominal Wall: Normal.
Bones: No significant pathology.

Additional Significant Findings: None

IMPRESSION:
1. NO ACUTE ABDOMINAL PATHOLOGY. NO ENHANCING LIVER MASS.
2. BENIGN CYSTS IN THE RIGHT HEPATIC LOBE AND UPPER POLE OF THE LEFT
KIDNEY.
3. INDETERMINATE T2 HYPOINTENSE LINEAR STRUCTURE ALONG THE
ANTERIOR WALL OF THE GALLBLADDER FROM THE NECK TO THE FUNDUS,
GREATEST IN THICKNESS AT THE FUNDUS WHERE IT MEASURES 7 MM. THIS
COULD REPRESENT ARTIFACT FROM BILIARY EXCRETION OF EOVIST, OR
POSSIBLY SOME SORT OF VASCULAR STRUCTURE. LIKELY BENIGN OR
ARTIFACTUAL, BUT A FOLLOW-UP WITH A GALLBLADDER ULTRASOUND IS
RECOMMENDED WITH SPECIFIC ATTENTION TO THE ANTERIOR WALL OF THE
FUNDUS.