Question about Lumbar Puncture Results

[AmandaM1982]

Hi Everyone!  My husband recently received the results of a lumbar puncture and we do not fully understand. We got the results, met with his neurologist, and then moved across the country the next day. We did not like that neurologist so are working to meet with another one. In the mean time, has anyone heard of or understand these results?

Zero (0) oligoclonal bands were observed in the CSF. However one (1)
paired band was observed in both the CSF and serum. Paired bands
suggest an immune response to an inflammatory process outside the
CNS and are unlikely to represent a CNS demyelinating disease.

Thanks for the help!
Amanda

[supermum_ms]

Hey Amanda,

Demyelinating diseases like MS cause 2+ or 4+  (depending on the lab) unique oligoclonal bands which represent immune response to an inflammatory process 'inside' the CNS.

From my understanding of what youve posted, if the results showed only 1 paired oband, so in the CSF and the serum, these results would be pointing away from demyelinating diseases like MS is and towards a causation that is 'outside' the CNS.

Hope that helps.......JJ