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Excedrin

My husband is addicted to Excedrin.  He now gets diarrhea a few nights a week and when he doesn't take it he says he gets an unbearable headache/migraine.  He says he can't quit because the headache is too unbearable.  So instead he just pops immodium to help the diarrhea.  How can he quit this?
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Avatar universal
I too was addicted to Excedrin. My neuro. doc. told me I needed to stop. So I told him I'll go cold turkey. That night was horrible. I was sweating so bad, was ice cold and my head hurt so bad. But I made it through and am so thankful I did it. It wasn't easy.
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Avatar universal
I have tried to wean myself of excedrin, and unfortunately I keep going back to it.  I take an obscene amount every day... three every two to three hours.  As time goes on I have to take more and more to get relief.  I have been on steroids from my neurologist to help come off, as well as numerous other daily meds.  I am saddened that we are all here with the same problem but a bit relieved its not just me.
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Avatar universal
Yes I will bet he does get a headache without it. It is called caffeine withdraw. Excedrine has tons of caffeine, which is addictive, though not usually psychologically, and once your body becomes dependant on it, you will notice symptoms like headaches. Same goes for religious pop drinkers who stop suddenly.
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1 Comments
I should have clarified. If you suddenly stop taking in these large quantities of caffeine, you will get headaches. Also depends on what kind he takes. Some has only acetaminophen and caffeine, and some adds aspirin to those. Aspirin will destroy your stomach, but if he is taking the kind without, it should not do stomach damage
20621916 tn?1502140720
Have him checked out for what is causing the headaches. He could get a doctor to prescribe generic Fioricet (Butalbital/Tylenol/Caffeine).  They also have cured headaches with Botox shots that last months.
Excedrin or Excedrin Migraine has Tylenol/Aspirin/ Caffeine.  The aspirin isn't good for the stomach and thins the blood.  I had an uncle who had bad arthritis.  Doctors were no help.  He took aspirins all the time.  He got a stomach ulcer, had to go into surgery and bled to death. They should have given him a pain killer, but they are so worried about pain meds. Do no harm ?
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Avatar universal
I am also addicted to Excedrin and have been for many years. I have suffered from headaches since my teenage years and when I started taking Excedrin about ten years ago I also thought...This is a miracle drug...Fast forward ten years later i've had bleeding ulcers...A blood transfusion...I still can't stop. I buy the off brand Excedrin from Walmart and take anywhere from four to six a day...I don't know how to stop bc when I do I have withdrawals! People should be aware of this very real dependency.
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Avatar universal
I just wanted to thank all of you on this forum. You have helped me get through a 21 hour brutal eye/skull-vice headache last Sunday after quitting Excedrin cold turkey.

I am 46 and have had chronic headaches since I was about 30. I don’t remember when I first started taking Excedrin Migraine, but it was early on, and I do remember thinking it was a near miracle drug for being able to promptly eliminate headaches that prior to Excedrin I could never seem to control and that would last for many hours or all day or several days. I have tracked my headaches for the past 11 years and there has been a mostly steady and insidiously gradual increase in the frequency of my headaches over that time. This is the average number of headaches per week over the past 11 years: .94, .87, 1.27, 1.02, 1.94, 2.19, 2.58, 2.13, 2.19, 2.60, 2.75, and 2.91 so far this year. I normally take two EM when the pain gets to about a level five out to ten. Ten being “I’ve just been stabbed in the gut”, like post-surgery pain, and five being “OK, now it is severely interfering with work and life and I need to shut down normal activity”. Two EM almost always knocked them out. Great, except the frequency was increasing and that was troubling to me. Also, over the past year I have found that occasionally I’ll have to take a 3rd one maybe 5 or 6 hours later if there was no improvement. Again, troubling. The tricky bit was that often (like many of you have mentioned) I would get maybe a level 2 or 3 headache, what I always called background headaches. I could still work and function, but the pain would just sit there for hours or all day annoying the hell out of me and probably making me not so fun to be around. I would normally only take EM if the pain escalated to a 5, but sometimes the background headaches would just go away on their own, but not always. Damn mystery. However, if I had a background headache, and I knew I had something big coming up where a level 5 headache escalation would not be tolerable, like a concert, movie, football game or large family function, I would go ahead and take the two EM just to knock it out preemptively. And it would. Also, over the years, I have not found predictable triggers for my headaches, despite tracking them for so many years. The weather and barometric pressure doesn’t seem to coordinate, nor does time of day (I get them any time day or night), time of year, stress levels, nor food. About 8 years ago, I had a bacterial overgrowth in my small intestines that was finally cured with antibiotics, but prior to finding a cure I went on an elimination diet for about 4 months to try to determine what food specifically might be causing me GI problems. I trimmed my diet down to about ten foods. No sugar (that’s a bugger to try to eliminate), no chocolate or other caffeine (other than EM), no gluten, no dairy, no preservative or additives and on and on. Plain meats, eggs, a few vegetables and lots of rice, maybe a few nuts. I never did figure out a food that was causing the GI problems, and the antibiotic (Rifaximin) did fix it immediately, but what I found interesting was that my headache frequency stayed the same during the elimination diet, so that made me think it wasn’t a food that was causing the headaches. Even when I was on those very few foods, I would eliminate each one of those for a while and again, no headache relief. Also, location doesn’t seem to act as a trigger. I get them at home, at work, on vacation on the other side of the country. So again, I am stumped as to a trigger. I do have an annual physical and I have talked with my doctor about my headaches, but he never seemed too concerned when I was having up to and around 2 a week. This past year it ramped up to 2.75 a week and so my doctor had me try propranolol for 3 months. No effect and actually a few more headaches than before the propranolol. Then he tried upping the propranolol and adding duloxetine (Cymbalta). That only lasted a week as I was VERY nauseated taking that. So after three months of getting those out of my system, I went back to the doctor and he suggested maybe it was rebound headaches. He had suggested that in the past, but he also thought I was not taking enough to cause rebound headaches (about 5-6 EM per week). But he said, since the other preventive medications weren’t working, he thought I should try stopping the Excedrin. Uh, scary, but OK. My last Excedrin was June 8, I had the appointment when he told me to stop on June 11 and for a couple of days, nothing. Wow, cool. Ah, then Sunday June 14, 12:25 AM. Right to level five. Eye vice. Unbearable. So I got an ice pack and was determined to fight through it. Then the crazy thoughts get in my head, like what if it keeps escalating to a ten (or above), what if it never goes away. By about noon later in the day, with no relief after 12 hours, I was desperate and almost took more EM. Instead I got online and did a search for “quitting Excedrin” and found this page. Holy crap, I am not the only one dealing with this. I can’t begin to express how much reading all of your posts meant to me. So, after reading, I was more convinced I was having rebound headaches from the Excedrin and was determined to tough it out. I am very much an all-or-nothing, cold turkey kind of person. I suppose I could have tried tapering off, but that’s not who I am. Finally at about 9 PM it went way. I mean gone. Not even a background headache. Whoa, this was extremely liberating and probably the first time in 16 years a level five headache has gone away without taking EM. Also interesting that the headache never escalated much above a level 5 as I feared it would. That was reassuring. Yes it was 21 hours of hell, and I was damn glad it was a Sunday – I would have had to take off work otherwise, but it did go away on its own. I did have a background headache for about 4 hours a few days later, but it went way on its own and now it has been 8 days and no headaches. Now I’m not naive enough to think they’re gone forever, and I have no idea how I’ll handle another one like that, but for now, this is different, better, and I’ll take it. I also realize my dosage was a lot lower than many on here, but when I read your posts and look at my progression over the years, what I am reading is my probable future without some action. I am hoping now, having stopped EM, that if and when the headaches do come back, I (and my doctor) will be better able to analyze any causes or triggers without EM overuse and rebound headaches clouding the assessment. Anyway, thank you all again. Sorry this is so long. I did mention I was an all-or-nothing kind of guy. Hoping for the best for all of you.
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2 Comments
I've had headaches and migraines all my life. I'm now I'm menopause and it's worse! I started researching because Excedrin starting hurting my stomach. I found cbd oil from a hemp store. I can't say enough about it. Please give it a try. I've quit Excedrin and went thru all that crap too but this oil is amazing. Its a roll on and they have other kinds too. Just Google it. I wish the best for you and anyone that suffers from background or migraine headaches. It has been a game changer for me!
Exactly how does it work?
Avatar universal
I am also addicted to Excedrin  - 58 yrs old, taking one a day for about 12 years.  Did you ever kick the addiction?  If so, I'd love to know how. I thought it may help for me to wean myself by taking 3/4 tablet for several days, then 1/2, then 1/4 etc.  Would love to know if you had success in going totally off of Excedrin.  I think they should have to put on the bottle that it is very addicting.  There are no warnings that I know of.
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1 Comments
I went cold turkey and got off it. It wasn't fun, but it was worth it.
Avatar universal
I have been a reader of mercola.com for years.  I would suggest you all try eft.  It is a simple way to correct the emotional reason for addiction.  It is nothing short of amazing.  It seems weird at first, but once you do it and get results, you will also find it amazing.  You can learn it for free so this is not someone out to make a buck although there are many practitioners out there to help.  You can go on youtube and find many tap alongs as well.  Just search "eft addiction"  Here is a link from mercola.com - http://articles.mercola.com/sites/articles/archive/2006/04/15/a-new-way-to-conquer-addictions.aspx
I also find Robert Smith from faster eft to be a very good resource.  Search for him on youtube as well.  Many of his earlier videos are very helpful.  The cdc says up to something like 80% if physical problems have an emotional basis, this will help remove the emotional issue.  Hope you find this useful, it will change your life.
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Avatar universal
Another Excedrin Migraine addict of many years here, and a coffee drinker to boot.  This is my second day off EM but I was hurting so much at the grocery store, I picked up some Tylenol Arthritis which helped, along with a nap.  I know the evils of Tylenol but it doesn't seem as scary or addictive as EM.  Hoping to get off OTC pain meds altogether, but can't do it without a small amount of relief.  Coffee helps some but should taper off on that, too.  I'm also on omeprazole for reflux--but it's getting better already without the acid of EM.    

Rebound headaches have been awful; plus my heart would pound and I felt fuzzy-headed with low energy.
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Avatar universal
I am on the raw foods diet.  On the diet I still have some chronic headache pain but no migraines.  I now am feeling pretty good and have started to wean off the 3 generic Excedrins a day.  I have taken Excedrin for 39 years.  For a long time I took 12 a day.  I weaned down to 3 because I thought I had a bleeding ulcer.  Now I see red marks on my arms which my husband said are due to bleeding under the skin due to the blood thinning effect of aspirin.  The red spots then turn to brown spots.  I'm much too vain to put up with this!  I am so glad nothing worse has happened to me!  I now have 1 Excedrin and two cups of coffee a day and plan to go to just coffee soon and then wean off that.  (then maybe I can go off the prescribed sleeping medication I take due to caffeine making me so hyper!)  What a mess!  This has been so convoluted all beginning with simple coffee causing chronic headaches and migraines which were "relieved" by Excedrin!  And 39 years later!  And really...without the raw foods diet I still would not consider giving up the generic Excedrin.  I thank you all for your posts and the hope you give me. I will probably read your posts over and over for awhile.
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Avatar universal
Hi well I think EXCEDERIN IS ADDICTIVE IM 34 STRUGGLING WITH THYROID DISORDER AND LEFT WITH HIGH BLOOD PRESSURE FOR THE REST OF MY LIFE I HADN'T TAKEN EXCEDRIN FOR A WEEK I'M SUFFERING MIGRAINES AND MY BODY IS ASKING FOR IT BUT I GAVE UP COLD TURKEY YES IT IS VERY ADDICTIVE STOP NOW THAT YOU CAN I WISH I WOULD HAVE NEVER TOUCHED THEM DUMB A@@ PILLS
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Avatar universal
I see the comments and it relates strongly to me.For years, I was a heavy, everyday user of Excedrin PM. Not for physical pain, but for wanting to sleep. I hated being awake because it was so depressing (still do), so as soon as I would wake up, I would take a bunch of PM (various brands, but always as strong as I could find). By the time I stopped a year ago, I was taking 20 at a time, 4 times a day. Apparently from reading here, that is a lot (and no those aren't typos or lying for effect).

By the time it was coming to an end, My weight was down below 100lbs (I'm 5ft 5), due to a lot of throwing up. One time, suddenly all of my hearing stopped in one ear. I mean everything, and that lasted a full week. My left ear still rings non-stop a bit, but I've learned to ignore it. My teeth starting weakening and falling out and I now look like a meth addict (making me pretty much unemployable). I was so weak, I would sit and shake for hours; my handwriting resembled a 3 year old drawing. My memory was shot: For example, I could be talking to someone and I would start to reply. But then halfway through I would forget what I was saying. And then I would flat out forget what I was even responding to at all. As if the other person said nothing. My eyesight started to go. First slowly, but then in recent weeks/months, it has gotten a lot worse really fast, within 2 months my left eye has gone completely useless. I coincidentally have a dr appt today about it, but my last one, they couldn't even do a reguar eye test on it. They did something called a CFF test, and I measured a CFF2, meaning I Could read fingers 2 feet in front of me (but to be honest, it was still guesswork based on shadows).

Then a year ago, I figured I had to admit that the PM were causing the problems, so I just stopped. Felt like garbage for a few days, but it was never really a challenge to stop. I just did. Now, can I say that these symptoms are all from the PM? Not at all, especially since all the teeth falling out happened after I stopped. But, there was nothing else going on in my life, and I was taking upwards of 100 pills a day on some days. In the year since then, I've seen almost no real information that doesn't sound like just generic butt-covering that too much PM could lead to these problems, so maybe it is just a coincidence. I don't know. I do still wish every day I could find something that allowed me to fall asleep as soon as I wake up.

And they really didn't help me sleep, either.
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Avatar universal
I'm a 68 year old male in very good health....except for daily headaches.  I do not drink coke or coffee and drink decaf tea.  I started with Extra Strength Excedren (WM Equate) about 15 years ago from work stress headache at base of skull.  That is where all my headache pain is....very tight muscles at top of shoulders and base of neck..  Do not have any migrane symptoms.  I took daily.  At max, I would take 2 pills 3 x per day.  Retired about 8 yrs ago, but I was already addicted.  Went to Headache Clinic 5 yrs ago and they said it was rebound headache but NO mention of caffine.  By chance I determined it was the caffine. For past few years, been taking about 4 Excedren pills a day....sometimes 1 at a time, sometimes 2.  Last month went back to Clinic and Dr prescribed Elavil to help get me off the Excedren (He told me about it's primary use).  Anyway, I take 20 mg each night.  Within the last month, I have reduced use of Excedren by taking straight caffine pills, generally 300mg total for a day.  For last 3 days, zero excedren and 100 mg caffine 3x per day (one early morning, one around noon and one early evening).   Headaches are generally under control with the 300 mg daily straight caffine.

So................is daily 300mg of caffine better or worse on my body than 3 Excedren pills with total of 195 mg (65 mg caffine per pill).  If equal, I get slightly better results with the Excedren and would probably switch back to that.
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Avatar universal
WOW! It is glorious to find others who suffer with this problem as it gives me hope that I can lick this addiction.

I've suffered with migraines for over 30 yrs. I've been on every prescription medication there is for migraines and nothing ever helped.

I'm 61 now and have been using Excedrin for migraine for around 10 yrs. I can't say I have a specific amount I take but I know it is way too much. Lately I've been having too many moderate headaches, nearly every day and a bit of diarrhea now and again. I use to chalk it up to the beginning of a migraine do to the weather or chocolate as they are both bad triggers for me, but now I'm sure they are rebound headaches. Not sure if the diarrhea is a part of it or not, but most likely is.

Wish me luck! Starting tonight I'm going to try and stop taking it a little at a time as I don't think I could handle cold turkey.
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Avatar universal
My husband weaned himself off excederin and caffeine after 10 years. It took 2 months before there was significant improvement so please be patient.  Now that his headached aren't as frequent and he is not numbing himself with OTCs he has also discovered a number of food triggers that have contributed to his hjeadached (wine, cheese, nuts, sweetners).  good luck!
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Avatar universal
I am a registered nurse who took Excedrin for YEARS for  migraines. I will tell you this. Your addiction is to the caffeine in the Excedrin. And coming off of them is equivalent to tying to stop drinking coffee. The horrible headaches from not taking them is the rebound effect. You need them to stop the headache from NOT taking them. You have to wean yourself slowly. Plain and simple. And the stomach issues are common as well as aspirin is toxic to the stomach.  The only reason I had to stop taking Excedrin is because I developed an allergy to caffeine. My heart goes into an abnormal rhythm from any form of caffeine in any quantities. Sad, I know cause Excedrin was my savior when it comes to my migraines.
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Avatar universal
I use Excedrin Migraine once an a while, is the only non-prescription medicine that works for me, but I understand all the concerns.  So what I do?  I reduced the dose to one, when are just starting the migraine signs, also I take baking soda with water to control the nausea and stomach bothering.  I meditate with frequency, and I void STRESS at all cost.  That is how I battle addiction, reducing the dose and be in harmony with everything.
I hope this helps.
PS: And I drink a lot of black tea...that is why I might not have diarrhea...(!?)
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Avatar universal
About 12 years ago i asked a doctor if it was possible to be addicted to excedrin and he called me everything but stupid.  Well I took it for 20+ years and developed ulcers in my stomach, my stomach closed and I almost died.  They had to remove half of my stomach and some of my colon.  Then they had (as the doctors called it) re-route me.  I spent 6 weeks in a hospital and now I have a huge scar and bill.    It was from taken excedrin and yes I was addicted to them.  
PLEASE READ THIS IS REAL
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Avatar universal
I was addicted to Excedrin for many years and for a long time I thought it was probably only me, but as time went on I had a feeling I might find some stuff on the internet about it but I was too afraid to see any of it.  I didn't want to be told the truth so I hid it from myself.  Now I came across this and just as I suspected, there are many others who are having the same problem.  I want to tell you what finally worked for me.  

It was probably 15-20 years ago, I started taking excedrin when I would get a bad headache, then as time went on, I would take it when I just started to feel a headache come on, because I wanted to stave it off early.  Then I realized I was taking it more and more, just for even the thought of a headache, and eventually like so many posts I see here, I took it every day because if I didn't, I would get a headache because my body needed it.  

But I realized it was not only a physical addiction, but also a psychological addiction too.  I realized how the drug begins to feel like a friend, how I just could not bring myself to go without it, just because of the fear of the headache I thought I would get.  

Well after about 15 years, the excedrin was not working for me anymore; instead of the "energy boost" and happy feeling it had been giving me, I began to feel worse after taking it instead of better.  I felt sick and energy drained.  It didn't work as well on my headache anymore either.  I am pretty sure that I got some health problems from it.  I got the ringing in my ears that never would go away.  I eventually lost my sense of smell. I would get sore throat and sensitive lymph glands in my neck.  I was getting pain in my arms and muscles and weird prickly sensations on different parts of my skin.  Something (I thought maybe some organ) inside of my lower right side in my back, was sore... sore to the touch and just constantly sore just to move around.  I also had this feeling that the only way I could explain another thing I was feeling is my body felt like it was getting "crystalized".

Well I tried for two years to get myself off of the addiction; I tried bribing myself, tried doing it for different reasons' sake, tried praying, tried keeping a journal, tried telling myself that my "friend"(excedrin) had now become my enemy, tried everything I could, but had no success.  I now totally understand the problem of drug addiction.  If I was addicted to this "non addictive" over-the-counter drug, I could now understand the problem anyone would have getting off stronger addictive drugs.

Well I want to tell you I am now free of the addiction to excedrin and I guess I am addicted to something else in place of it, but it is at least not tearing down my health like the excedrin did.  I am actually getting better as time goes on.  I found Zipfizz.  I take one in the morning and one or two more throughout the day.  Sometimes if I really do have a headache when I wake up in the morning, I'll make a "double" right away.  They say you should not drink more than three of them in a day, but there are a few times that I have taken four in a day.  But there are days that only one does the trick and there are even some days I could go without any at all.

The hardest thing I think is really the psychological addiction.  You have such a hard time forgetting about taking the thing that you think you need.  It was like a security blanket.  It was such a scary feeling not to be doing the thing (taking the drug) that you thought was the only thing that would work, the only way you could go on and function.  
But there is good news...as you are successful to go days along without it, you slowly begin to loose the scared feeling and the security feeling about it.  I've had many days now that I actually have not even thought about it anymore.  That is such a good feeling, not to be so hooked to something.  It is the hardest battle I have ever fought.

One other thing that I found that helped me was to keep my rectum cleaned out with water.  I bought one of those suction things you get in the baby isle to suck out noses, and I squirt water into my anus after I go poop to clean it completely out of residue or poop left behind.  I know this sounds really weird, but I would actually start to feel slightly headachy whenever I know there was some in there to be cleaned out.  I have a feeling that I was so toxic from taking the excedrin all those years.  Your anus absorbs the water from your poop so I think that by keeping it clean there was not any toxin to be absorbing into my body.  Any feeling of headachiness would usually go away if I cleaned myself out.
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Avatar universal
First off, akitagurl12, there is an Excedrin recall by its producer, Novartis, because - to quote them - "the products may contain stray tablets, capsules, or caplets from other products, or contain broken or chipped tablets." Supposedly the drug will start returning to shelves in a few months, but for now its pretty much impossible to get the brand-name drug in stores - although you can buy it at greatly hiked prices on Ebay!

BUT: most drugstores carry a generic version of Excedrin, and it's pretty much the exact same drug with the exact same ingredients (Acetaminophen, aspirin, caffeine) with the exact same effect. Walmart's generic brand, Equate, calls their generic version "Extra-Strength Headache Relief Tablets", as does CVS.

Meanwhile, I have been an Excedrin addict for almost 30 years at this point, and I will post shortly about my own issues with the drug and addiction. But first I need to get some rest. It's been an extreme problem for me, and also an issue that's extremely hard to get support around - nobody takes me seriously. I'm wondering if some of the folks around here who have been able to acknowledge the problem can help me with my own struggle...
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2030769 tn?1343647674
Excedrin seems to be the only thing that help me when i get bad headaches and when i went to get more today, i was told by the store that all Excedrin products have been pulled from the shelf!?!?  Is there something going on?  I went to 3 different stores and found the same thing!
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Avatar universal
Update: I drank one 5hr 1/3 at a time for 3 days, then the second bottle 1/4, 1/4, 1/4, 1/8, 1/16, 1/16 (only drops at this point). Took a single ibuprofen if I felt a headache coming on in late morning. After this regimen, I am caffeine free with minimal headaches!

Finding it hard to avoid caffeine when eating out - no DC, iced tea, etc. #firstworldproblems
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Avatar universal
I guess I'm lucky. I've only been taking one tablet in the morning for the caffeine, for many years. My doc says no problem, and you're getting your aspirin too! But I hate being dependent on pills, and I only drink decaf cola, etc. never coffee . I decided to stop because the acetaminophen is bad, but stopping 250mg of daily asprin is also risky. The caffeine in Excedrin is equal to only 1/3 cup of coffee, same as a 5hr energy. So for the last few days I've taken 1/3 of a 5hr plus 2 baby aspirin (162mg), and I'll continue to cut for a couple more weeks until I've stopped altogether.

No problems at all yet.
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Avatar universal
Just went off Excedrine Migraine 9 days ago.  I am a very successful and well-educated woman.  I had been taking two pills a day for the last 4 years.  It started as a great way to avoid my migraines and then I got use to the "up" it gave me.  Well the withdrawal was horrible.  I felt like I had a concrete block on top of my head for the first 6 days....dizzy, disoriented (started my car and then was searching in my pocketbook for my keys!!), tired, pains in my neck, legs, arms, vivid dreams, woke up from one with my teeth clenched so tight I had to concentrate to open my mouth!  Needless to say....I got scared and made a Dr. appointment yesterday.  I was embarrassed and scared to tell him what was going on with me.   Well...he had heard my story many times before and said he had a patient who had to "check out of work" for two weeks to get off the stuff.  He said I am experiencing Rebound headaches.  He said my pain level and tolerance have been compromised by the excessive use of Execedrine.  He gave me some relief by telling me I should be over this within three weeks if not a little longer.  He suggested I take an Aleve to take the edge off the headache, as it would not make the Rebound headache totally go away.  It has helped somewhat.  The "fog" that I have been in is SLOWLY starting to lift.  To anyone who reads this....Do not give up!!!!  It will get better!!
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