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telaprevir bound to protease(gray) and 4 sites at which mutations enable resistance (Chao Lin VRTX)
telaprevir bound to protease(gray) and 4 sites at which mutations enable resistance (Chao Lin VRTX)
Comments (2)
223152 tn?1346978371
frijole, Jun 03, 2010
Willing, I don't understand this but it doesn't sound good. I wish they could profile patients who could be subject to resistence
frijole
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cookie2554, Jul 06, 2010
OK Willing:
Barb here, the RN post Tx pt with an acute rebound of hcv after 3 nonresponder trials with interferon prior to Tx.
Its been years since I studied genetics ,etc. yet I know my virus must have mutated each time I was treated with SOC
So explain in somewhat more simpler terms how mutations enable resistance. I am hoping to get early access to DAA's ( hopefully the Inform trial meds or something similar if better ) without interferon but if that doesn't happen I may have to resort to teleprevir or boceprevir with Interferon. This is what I am told even though previously I was also told I was sensitzed to interferon and should not go on it again. Do these DAA's have the same risks? Do you know? thanks so much again for all your info. Cookie 2554
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