Not only are shopping carts touched by hundreds of hands daily (and by a few mouths and tongues of youngsters sitting behind the handlebars), but they also harbor harmful bacteria like Salmonella and E. coli, states ABC News. Before you begin your shopping spree, wipe down the cart handle with a disinfectant wipe, which many grocery stores now provide. And don't pop any food like free samples in your mouth without washing your hands first.