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Is it safe to do an herbal colon cleanse/detox while taking an SSRI (Zoloft)?

I am currently taking Zoloft for depression and anxiety and am preparing to do a detox colon cleanse. Is it safe to do a all natural herbal detox colon cleanse while on Zoloft as long as the Zoloft is taken a few hours apart from all other supplements? Some of the herbal supplements are as follows, Calcium bentonite clay, psyllium husk powder, Molybdenum, milk thistle, black walnut hulls, grapefruit seed extract, clove bud, pau d'arco bark, pumpkin seed, myrrh gum, turmeric root, garlic bulb, hyssop, gentian root, elecampane root, prickly ash bark, yellowdock root, fenugreek seed, peppermint leaf, false unicorn root and other similar cleansing herbs. My doctor is COMPLETELY void of any knowledge of natural treatments so I can't get any answers from him. Please help! Thank you!
Best Answer
1756321 tn?1547095325
None of these ingredients you mention are listed under an adverse interaction to zoloft.

The following supplements taken with Zoloft may cause undesirable or dangerous results:

5-Hydroxytryptophan (5-HTP)
L-tryptophan
St. John's wort
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Avatar universal
This is going to be late for you, but you should never take liver cleansers while taking medication.  What you're describing is a combination colon/liver cleanse.  Milk thistle and yellowdock, for example, are liver cleansers, and could theoretically wash some of the medication out of our system, as the body sees virtually all medication as toxic.  There are colon cleanses that don't contain liver cleansing herbs, just colon cleansers, which are abrasives and sometimes laxatives that are intended to clean out that system.  You might want to look into those next time.
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Avatar universal
Thank you!
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Avatar universal
Don't waste your $$$ on a colon cleanse you and everyone else don't need it except for a colonoscopy!
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