If the spot is on the iris, the colored part inside the eye which surrounds the pupil, it may be a nevus, a benign pigmented spot. Ont he other hand it could also be melanoma which is a form of cancer of pigment cells. As has Dr Coyner, I recommend seeing a boarded ophthalmologist.
I recommend evaluation by a veterinary ophthalmologist (www.acvo.org). This may be bullous keratopathy, which is a defect in the cornea that can progress to ulceration and rupture if untreated.
Kimberly Coyner, DVM DACVD