I have bilateral intermediate grade DCIS (1.5 cm on left, .5 cm on right). After a number of surgeries I have +1cm margin on right, but around 2mm margin on the left. On the right I have ADH transected at the specimen. On both right and left I have plenty of other proliferative changes including atypical lobular hyperplasia, more ADH, cysts, adenosis, fibroadenoma, etc.
I am preparing for bilateral radiation but concerned over the margin on left and remaining ADH on right. I am 48 and the DCIS is ER and PR positive, so I would take Tamoxifen.
Am I at an increased risk of local recurrence based on 2 mm margin, my age (premenopausal) or known ADH remaining in breast or does the whole breast radiation take care of these issues (well, except for the age)?
Thanks.