Aa
Aa
A
A
A
Close
Avatar universal

need help understanding pathology report

help with interpretation of path report

as follows:

Right breast
Infiltrating ductal carcinoma (2.1) grade 3 located in the upper outer quadrant with peritumorial lymphatic invasion. and extending to 1mm from the deep margin and 2mm from the anterior magin.

Dutal carcinoma in situ focally extratumorial ( primarily localized to the main tumor mass with separate focus in the inner lower quadrant) high grade, located 5mm from the closest deep margin.

er, pr positive  her-2 negative sentinel nodes negative.

Not understanding statement peritumorial lymphatic invasion... confused is there or is there not lymph node invasion?  How does this differ from sentinel node?

I had changed my mind from original plan for lumpectomy and chose bilateral mastectomy with reconstruction.  Left breast prophlactic.  I am assuming this was a wise choice in the end due to the unexpected dx. of DCIS in addition to the known tumor prior to surgery.   thanks.  
2 Responses
Sort by: Helpful Oldest Newest
Avatar universal
Thank  you for the info.
I am 6 days post surgery.  Surgeon left for vacation  the day I was released from the hospital and will not return until next week at which time I would assume she will refer me to an onocologist.
All I have been told by Surgeon and PCP is that chemo will be require due to the grade 3 and my age.
I would not have know anything more execpt for obtaining a copy of my report.  
I am premenopausal/ perimenopausal ( in my 40's)  so from what I gather the chemo will put me into menopause.  
Will the grade 3 require a more agressive chemo or is that insignificant.
My mother also had BC at the same age as myself and passed away 8 yrs ago .... 17yrs. post diagnosis from brain mets she  initially had mastectomy, then radiation, chemo, tamoxifen.  I had the genetic testing done but it was negative.
I also have 4 daughters so my concerns are primarily that they gain as much info knowledge as possible.
Helpful - 0
242527 tn?1292449140
MEDICAL PROFESSIONAL
Dear chancleta:  The pathology report indicates that there is an invasive component (infiltrating ductal carcinoma) and a non-invasive component (ductal carcinoma in situ) to your breast cancer. It is the invasive part that will dictate most of the treatment recommendations.   Peritumoral lymphatic invasion means that there was evidence of invasion of cancer cells in the lymphatic vessels around the tumor.  It is not the same thing as a positive lymph node.  This finding sometimes indicates that there is a higher chance of cancer spreading to the lymph nodes , although it appears that in your case the sentinel lymph nodes were not involved. Being ER and PR positive suggests that this is a hormone sensitive cancer that may benefit from an anti-hormonal treatment. You should discuss the pathology findings with you physician including what it means in terms of further treatment recommendations.
Helpful - 0

You are reading content posted in the Breast Cancer Forum

Popular Resources
A quick primer on the different ways breast cancer can be treated.
Diet and digestion have more to do with cancer prevention than you may realize
From mammograms to personal hygiene, learn the truth about these deadly breast cancer rumors.
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.