The only physical symptom it can lead to is raw skin on your penis or a possible skin reaction to lubricants. It is totally unconnected to any immune issues. I suggest you address your anxiety directly as it may be adding to the frequency as well as being the main problem.
Is there possibly something else going on in your life that is the story behind the story of your anxiety?
tg
Until you get a response from the expert, perhaps you could check out the Men's Health Forum. I've seen some posts (from other forums) re-routed there when talking about masturbation. I'm sure Dr Ted Grossbart will respond when he is able.
J