I was taking 200mg per day of Triflucan during 2 weeks. It was very effective.
With me, fluconazole began to be effective at day 13-14. I was taking 1 tablet a day during 14 days. It continued to take action until 6 week after stoping the treatment. But the maximum effect was reached 3-4 weeks after taking my first tablet.
Hello,
Thanks for writing back to me.
Both ketoconazole and itraconazole belong to the “azole” group of antifungal drugs. Basically Itraconazole is more wide spectrum and less toxic than ketoconazole and has been hence used for a variety of fungal infections chief being aspergillus, blastomycosis, sporotrichosis, histoplasmosis, and onychomycosis and ketoconazole is often used for Candida, Histoplasma, Coccidioides, and Blastomyces (although it is not active against Aspergillus).
If the symptoms are responding to one particular group of antifungals and less to others then the type of fungal species can be narrowed down which can further be confirmed after fungal culture.
The amount of time for which fluconazole stays in the system depends on the dosage. It also varies with the body systems. On average it will be active in the body for about a week. Hence consult your dermatologist and get the fungal culture repeated only when he /she advises.
Hope that this information helps and hope that you get better soon.
Wishing you good health.
Thank you very much, I will do these tests soon.
As my rash improve a lot with itraconazole and fluconazole but not with terbinafine and griseofulvin, could we determinate what mycosis it is ?
How long after taking oral fluconazole I have to wait to do the tests ?
Thanks.
Hello,
Thanks for posting your query.
I can understand your concern for these symptoms and from the description of your symptoms and the positive response to oral antifungals, it looks like the etiology is fungal in nature. It is less likely to be eczema which responds to oral steroids.
In new eczema, the affected skin appears red and elevated with small blisters which break and the affected skin will weep and ooze. In older eczema, chronic eczema, the blisters are less prominent and the skin is thickened, elevated, and scaling. However eczema does not respond to oral antifungals and responds best to topical and oral steroids. In your case there is worsening of the symptoms with steroids which is usually present in cases of fungal infection as fungal infections are exacerbated with use of steroids.
One possibility which comes to my mind is of confluent and reticulated papillomatosis and fungal causes have also been proposed to be one of its etiology. Lesions start as hyperkeratotic or dry lesions which coalesce to form a reticular pattern and usually occur on the trunk, axillae or face.
My sincere advice would be to get a wood lamp examination, KOH examination and fungal culture of the skin scrapings and a biopsy of the effected skin done to confirm the diagnosis. Biopsy skin should confirm the cause.
Hope that this information helps and hope that you get better soon.
Wishing you good health.