I have been diagnosed with Zoon's Balanitis, or Plasma Cell Balanitis. I am male, 35, uncircumcised. I'm not a diabetic, and I've been tested for most STD's, which were all negative. Just weeks ago, I was sent to get a urine culture. Though initially tested positive with traces of bacteria, when retested again for bacteria culture, the results came back negative as well.
I have been battling this inflammation for almost 19 months now. My first occurrence of any penile inflammation was a month after I had unprotected sex, when I noticed a foul smelling substance (smegma) underneath my foreskin. My primary physician told me it was a yeast infection, and that it can't be from sexual transmission since the yeast fungi can't be dormant for that long. He recommended OTC clotrimazole. I followed the treatment, and after a full week, went back to my primary to let him know that it wasn't working. He sent me over to a dermatologist, and I was told that it was a fungal infection and to apply Lamisil, the OTC anti-fungal cream. Within 3 days, the infection/inflammation cleared up and went away, or so I thought...
For 2 months, I was cleared of all symptoms, no smegma, no irritation or itching. But little red dots were always present on the glans. Then after 3 days of hard drinking and insomnia because of work obligations and jet lag, I noticed the itchy irritation and smegma buildup once again. I was out of the country at the time, but I knew exactly what to do - Lamisil. Only this time, it didn't work. When I came back stateside, my doctor tried everything that he could think of: OTC hydrocortizone cream/ointment, OTC antibiotic cream, oral antibiotics (Ciprofloxacin), anti-fungal cream (Lamisil, Clotrimazole), oral anti-fungal (Diflucan). I just tried Tacrolimus after researching extensively online, and that's failed me too. I'm extremely depressed. I've seen 3 primary physicians all together, and 1 dermatologist, and still, no solution.
The dermatologist advised that Zoon's Balanitis is idiopathic, and that it may persist or it may go away on its own, and to keep the area clean and use hydrocortisone as necessary. I tried washing twice a day, morning and night with Cetaphil, a mild soap, but the condition would inevitably relapse if left unmedicated. The only relief I get is from OTC triple antibiotic from Walgreen, a Neosporin equivalent. The active ingredients are Bacitracin Zinc, Neomycin Sulfate, and Polymyxin B sulfate. If I apply this for about 3 days, once a day, I can stave off the balanitis for about a week, then the symptoms would slowly relapse, beginning with the presence of smegma, then the overall redness on the glans and foreskin with dark red and well-defined patches at the base of the glans. and last comes the transverse lesions at the base of the glans near the crease. I've been doing this antibiotics on and off for about half a year now.
Not only am I curious to find out what active ingredient in the ointment is effective against the inflammation, more importantly, I wonder about the negative side affects, if any, of prolonged topical antibiotic use. Does my repeated use of topical antibiotics create the possibility that eventually, it too will be noneffective? If the Balanitis is responsive to topical antibiotics, could the underlying cause be bacterial? If so, is there a class of oral antibiotics containing Bacitracin Zinc, Neomycin Sulfate, or Polymyxin B sulfate (present in the cream/ointment) at a higher dosage that I should try? Or is Ciprofloxacin a "catch all" antibiotics? I did noticed when I was on Cipro that the Balanitis showed no improvement.
Can someone please help me? Am I going to have to live with this for the rest of my life? Or is circumcision the only cure?