Aa
Clearance among slow responders?
Good Day guys!
I was just wondering if there were people here who cleared/SVR who happened to be slow responders and Geno 1a's?
If there were people who tx'd for a second time and cleared. Of course being 1a's.
At my Dr's visit today, she did bring up the thought of maintenance therapy of interferon as a back up plan...a just in case. She said that a maintenance program of interferon would stop or at least slow down cirrohsis.
Are there those here who are such a program?
I mentioned that I would like to have another bx done at the end of this tx to see what changes have been brought about with doing 48 weeks ( possibly 72 ). She said that it really wouldn't be neccessary to have a bx done.
She did say that my VL on HCV was exactly 50. No more...no less. Does that mean then that I am UND or borderline? These results were given to me today from tests done back at the end of June.
If you guys could answer those questions that pertain to you or that you have knowledge on then I would really appreciate it. As always take care of yourselves......
Yours in Christ,
Rick
I was just wondering if there were people here who cleared/SVR who happened to be slow responders and Geno 1a's?
If there were people who tx'd for a second time and cleared. Of course being 1a's.
At my Dr's visit today, she did bring up the thought of maintenance therapy of interferon as a back up plan...a just in case. She said that a maintenance program of interferon would stop or at least slow down cirrohsis.
Are there those here who are such a program?
I mentioned that I would like to have another bx done at the end of this tx to see what changes have been brought about with doing 48 weeks ( possibly 72 ). She said that it really wouldn't be neccessary to have a bx done.
She did say that my VL on HCV was exactly 50. No more...no less. Does that mean then that I am UND or borderline? These results were given to me today from tests done back at the end of June.
If you guys could answer those questions that pertain to you or that you have knowledge on then I would really appreciate it. As always take care of yourselves......
Yours in Christ,
Rick
Hey Rick --- Here's sending you some super cheer and good wishes for your UND/SVR. OK?
Hugs,
Meki
Hugs,
Meki
Rick: She did say that my VL on HCV was exactly 50. No more...no less. Does that mean then that I am UND or borderline? These results were given to me today from tests done back at the end of June.
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Let's assume the worst -- or in this case the best -- and that your nurse is reading the results wrong. "50" is the sensitivity of many common PCR tests and is usually expressed as "<50". It does not mean you have 50 IU/ml's of HCV, it meand you are undetectible to the limit of the test. It's not uncommon that these tests are misread.
My suggestion is to get your own copies of the blood tests and then if any questions call the doctor to go over them.
Also, what week of treatment are these results for? Was this your first viral load test or did you have some before?
-- Jim
------------------------------------------------
Let's assume the worst -- or in this case the best -- and that your nurse is reading the results wrong. "50" is the sensitivity of many common PCR tests and is usually expressed as "<50". It does not mean you have 50 IU/ml's of HCV, it meand you are undetectible to the limit of the test. It's not uncommon that these tests are misread.
My suggestion is to get your own copies of the blood tests and then if any questions call the doctor to go over them.
Also, what week of treatment are these results for? Was this your first viral load test or did you have some before?
-- Jim
Rick,
yes, slow responder genotype 1A's DCAN clear. The first name that comes to mind is NYGirl. She did the 72 week TX and was still UND at her 3 month post-TX PCR.
i think she's due for her 6 month PCR next week so hopefully she'll post wonderful results!
I know I've seen posts from folk who cleared on a second round of TX.
If your Dr. said your VL was exactly 50, the issue of whether or not that's considered UND depends on the test she ran.
I know the older tests showed UND at below 615. Some of the newer tests go to 10, 5 or even 2.
You might want to ask for a more sensitive test.
About the 48 vs. 72 week tx; the studies show that slow responder 1A's decrease their odds of relapsing by extendung to the longer TX. I beleive the odds rise to 2 out of 3 instead of fifty-fifty; eg; 70% chance of SVR vs. 50%.
About another biopsy; if I thought my VL was 50 I'd want to have another, better PCR done first. I also might want to consult another Dr. Over the weekend, I'll pull up some links to the studies showing pluses of extended TX and flag you.
how's the new puppy?
wyntre
yes, slow responder genotype 1A's DCAN clear. The first name that comes to mind is NYGirl. She did the 72 week TX and was still UND at her 3 month post-TX PCR.
i think she's due for her 6 month PCR next week so hopefully she'll post wonderful results!
I know I've seen posts from folk who cleared on a second round of TX.
If your Dr. said your VL was exactly 50, the issue of whether or not that's considered UND depends on the test she ran.
I know the older tests showed UND at below 615. Some of the newer tests go to 10, 5 or even 2.
You might want to ask for a more sensitive test.
About the 48 vs. 72 week tx; the studies show that slow responder 1A's decrease their odds of relapsing by extendung to the longer TX. I beleive the odds rise to 2 out of 3 instead of fifty-fifty; eg; 70% chance of SVR vs. 50%.
About another biopsy; if I thought my VL was 50 I'd want to have another, better PCR done first. I also might want to consult another Dr. Over the weekend, I'll pull up some links to the studies showing pluses of extended TX and flag you.
how's the new puppy?
wyntre
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