forth shot tonight. no bad symptom yet. burning butt has got a little better, I tried some of the things advised and took care of the worst, some itching but not bad if I don't think about it, I got a couple small bumps on my shoulder almost like a blister but don't itch, have been a little tired but have been busy and not getting enough sleep, (10pm meds and 6 am meds don't leave much room for error). thanks for listening