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186606 tn?1263510190

Interesting news...Maybe I am going to clear?

Hi Guys:
I got the most interesting news on my second visit with my new Hep doc....

He has determined that I am in the recovery phase from an acute hepatitis B infection (probably acquired as well during my hospitalization). My liver labs are all normal.

But more interesting is that my PCR has dropped from 42,000 to 142.

He said "I think you are going to clear this. You have a two plus log drop in three weeks. Come back in three months"

This has been a crazy wild ride.

Thoughts?

Deb
11 Responses
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Avatar universal
Great news! God is good!
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Avatar universal
Congratulations. I'm so happy for you. Nothing like a new doctor for a new perspective.
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Avatar universal
So that I understand this correctly, the "142" refers to a Hep B viral load, as opposed to a Hep C? I don't know anything about Hep B but so happy your doctor things you are going to clear.

-- Jim
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186606 tn?1263510190
No, the 142 viral load is for Hep C....
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Avatar universal
OK. Then you are co-infected.

Did your viral load drop from 42,000 to 142 while on treatment or without treatment? If it was on treatment, curious what weeks were the two tests taken and what was your pre-treatment viral load? Genotype? Amount of liver damage? Sorry if you've covered this all before but I forget.

-- Jim
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Avatar universal
I'd be very cautious because if the doctor is wrong, and you don't clear it, you will have missed the "acute treatment" window and be considered "chronic" and you will have to treat longer. With acute cases it is protocol to start treatment right away within the first 6 months of contracting it because your chance of clearing the virus on a short course of treatment are very good. Once you are chronic, then you will be treating for a year if you are geno 1.

I hope you clear it on your own, but if you don't I'd hate to see you miss your acute treatment window.
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186606 tn?1263510190
Hi Guys:
Yeah, he said I got coinfected and probably about 3.5 months ago. My viral load dropped from 42,000 to 142 in the period between Feb 14 and March 1. This was without treatment. I have never had a viral load done before the 42,000 one. I am genotype 4. No liver damage. All LFTS normalized now. Four doctors now believe that I contracted these in hospital.

I will have another appointment right before the 6 month window closes.

What do you think?




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Avatar universal
I believe geno 4 has the same treatment course as geno 1.

That's a tough call. I'd be encouraged by the low viral load count however, viral load flucuates so much Im not sure how much that matters. What matters is undetectable or not.

I'd probably do the same thing, wait until my window of time was closing and see if I'd hit undetectable, if they found any virus at that point, I'd consider treating.
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Avatar universal
Treating acute Hep C is not the same as treating chronic Hep C and don't pretend to know all the in's and outs. In fact, doctors have far less experience in treating acutes so the protocols may not be all that established as opposed to treating those with a chronic infection. Some older studies suggest 24 weeks with interferon only (no ribavirin) but I really don't know the latest protocols. Unless your doctor is a very experienced liver specialist (hepatologist) who treats large patient groups, I'd seek one out for advice on this one. Especially because you appear to be coinfected. I doubt the average GI would know how to make the right calls here. Anyway, good luck. From this layman's vantage point sounds like your low viral load is a good sign, just keep on top of it since viral load during the acute stage is a bit wacky and can go in and out of the detectible range many times.

-- Jim
Helpful - 0
186606 tn?1263510190
you guys are the BEST!
I talked to my internist who is a wonderful person. He will run a pcr on me in a couple weeks and every few weeks after that. He is going to investigate a hepatologist in CA that he knows for a third opinion.
I'm seeing him tomorrow to talk more about this.

Again...you guys are the ABSOLUTE BEST!!!
All of You!
Helpful - 0
Avatar universal
Definitely see a hepatologist as soon as possible, I wouldn't wait much longer. Here's a good group in CA some here have treated with.
http://www.cpmc.org/advanced/liver/team/medstaff.html
Helpful - 0
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