what to expect

[mussygirl]

My mum was diagnosed with nsclc in October, she had a good response to chemotherapy but has failed a bit recently.  The weight loss and no appetite are the big worries as she is now almost skeletal. We were told at the last scan that it had spread to the cerebellum in the brain and they then gave her five days of radiotherapy.  She doesn't have many brain type symptoms but does have a tremor which is worse in the morning.  I feel she cannot go on like this for long and wonder what might lie ahead.  Any advice would be appreciated.

[Laura9236]

A related discussion, Adjuvant chemotherapy was started.

[Kamal S Saini, MD, MRCP (UK), DM]

Hi,
There is no evidence that any specific type of diet improves outcome.
Tablet Magesterol Acetate 40 mg 3 to 4 times a day has been to improve appetite in some patients with cancer cachexia.
I hope the visit to the oncologist is fruitful. Let me know how it goes.

[mussygirl]

Thanks, we know the prognosis is as bad as it could be, any tips to build her up, we have tried drinks (which she doesn't like), high calorie foods etc., but she just has no appetite, should we just accept this or continue to try different foods?  I am worried that she may go on to develop other brain symptoms as working in nursing have seen patients like this before - it's very different when your own mum is facing this. We are back at the oncologist today don't hold out much hope that she will offer us anything.
Anyway, thanks for this forum which gives somewhere to ramble a bit and ask questions.

[Kamal S Saini, MD, MRCP (UK), DM]

Hi,
NSCLC which has spread to the brain is at an advanced stage, and carries a poor prognosis.
The tremors are most likely because of the cerebellar metastases.
If her general condition is reasonable, she may be started on next-line chemotherapy. If she is not doing so well, then oral medications (EGFR blockers) or monoclonal antibodies, clinical trials, or best supportive care are options.
In all cases, supportive therapy to address issues of nutrition, infection, cough, and dyspnea must be provided.
All the best, and God Bless!