I am a 51 year old female. I have asthma, controlled now, and sleep with a CPAP machine. For several years I've had severe spasms in my arms and hands. They come on unexpectedly. Sometimes I throw pens or forks. Sometimes I simply can't hold such objects because of recurring spasms. Sitting on my hands seems the only way to keep them from spasming. The spasms extend into my forearms. I also get horrible cramps in my legs at night. These cramps center in my upper thigh and are acutely painful. The only relief I get is to stand on the affected leg and try to walk it off. If I stop walking too soon, as soon as I take my weight off the leg, the cramp returns. Recently, I've begun to experience a burning pain around the ankles at times. (They sometimes swell). Is all this vascular? I was diagnosed with some rare condition of the vessels of my brain 2 years ago. Apparently the walls of my vessels are unusually thick. Perhaps this extends to other vessels in my body? My spinal column is also only 80% the diameter of the average person's.