My husband is a 38y/o white male, normal weight. About 6 months ago he had an episode in a movie theater that he described as severe dejavu & confusion. He got dizzy & kind of zoned out for about 5 minutes. He did not become unconscious, but he felt dizzy & had a headache. We went to the ER & all tests (CT, EKG, Neuro exam, Cardiac enzymes) all checked out fine. He continued to have severe headaches, confusion & dizziness especially in the evening. He was prescribed Topamax, which helped initially, but began to cause him severe chest discomfort. He stopped taking it at a cardiologist recommendation. He has been scanned from head to toe. MRI/MRA of the head & neck, CT of the chest & abdomen, 3-day EEG, heart echo & stress test, all normal. He had a Lumbar Puncture & the results showed an elevated IgG antibodies & a total protein of 116, all other values were normal. His neurologist tested his CSF for syphilis, it was negative. He continues to have headaches every night & these past 6 months have beyond difficult, neither of us have been able to work & are frustrated at not being able to find an answer.
Does anyone know what an elevated IgG level & total protein in CSF could mean in the absence of other indicators? Any help would be greatly appreciated. Thanks.