The antibodies mean underlying autoimmune thyroid disease -- in your case, Hashimoto's in its early stages (still a relatively normal TSH). However, with the family history and some research that links an increase in thyroid cancer to Hashimoto's and slightly high TSH levels, a repeat ultrasound and FNA of any/all nodules noted that appear enlarged or suspicious would be indicated. Also consider thyroid medication with these issues with a target TSH of around 0.5-1.0.
I am just a patient, not a doctor.
My TSH was recently 2 something as well and my TPO antibodies are over 1200 and Tgab are also elevated. So yes, it can be normal in the presence of antibodies. One year ago, they put me on thyroid meds because of 1.4 cm nodule, heterogenicity, strongly positive antibodies and TSH (briefly +5 at one point) and I went "instant" hyper. Have been happily med free since November.
2 cm nodules would need biopsy. Did you mean cm or mm?
2mm are likely too small to biopsy but would eventually be followed up with ultra sound I think- but I don't know how often.
I have recently been diognosed with graves disease my tpo antibodies were 3,000 my T4 is 49 and i can't remember what the other levels were one was 0.5 but not sure what it was called should i be concerned.