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High Liver Enzymes
I have liver enzymes coming back at 240...no one can figure out WHY? they started out at 167 in august 2010 as of November 2010 they are now 240...has mri's, ct scans, hida scan, ultrasounds, liver biopsy, all sorts of blood tests...WHAT COULD BE wrong that my doctors are missing? PLEASE help i am very desperate at this point!!!!
MEDICAL PROFESSIONAL
Hi
Welcome to the MedHelp forum!
Not sure what you mean by liver enzymes. Many a times AST (SGOT) and ALT OR SGPT (both are collectively called transaminases) rise without any cause. Because AST is found in many other organs besides the liver, including the kidneys, the muscles, and the heart, having a high level of AST does not always (but often does) indicate that there is a liver problem. For example, even vigorous exercise may elevate AST levels in the body. However to reach at that conclusion the medical causes of these raised transaminases have to be ruled out. Causes of liver transaminase elevations include viral hepatitis, alcohol use, medication use, steatosis or steatohepatitis, and cirrhosis. Steatosis and cirrhosis are ruled out by the ultrasound. Other common health conditions, such as diabetes, heart disease, pancreatitis, hemolytic anemia and thyroid disease, can also cause liver transaminase elevations. Most liver diseases are characterized by greater ALT elevations than AST elevations except cirrohsis and alcohol abuse. ALT also rises in bile duct obstruction due to stone.
Raised alkaline phosphatase (The normal range is 44 to 147 IU/L (international units per liter).is often found in a growing child and at puberty. There are several bone disorders too that can raise this enzyme like rickets, osteomalacia, Paget’s disease of the bone, tumors, metastasis and recent fracture. An elevation in AP is often seen in cholestatic liver disease, bone disease, and occasionally with inflammatory bowel disease. In an otherwise healthy individual a rasied AP could be due to false positive test and the test should be repeated. If it is still high then other mentioned causes should be ruled out.
Please consult your PCP for primary examination followed by proper referral.
Take care!
Welcome to the MedHelp forum!
Not sure what you mean by liver enzymes. Many a times AST (SGOT) and ALT OR SGPT (both are collectively called transaminases) rise without any cause. Because AST is found in many other organs besides the liver, including the kidneys, the muscles, and the heart, having a high level of AST does not always (but often does) indicate that there is a liver problem. For example, even vigorous exercise may elevate AST levels in the body. However to reach at that conclusion the medical causes of these raised transaminases have to be ruled out. Causes of liver transaminase elevations include viral hepatitis, alcohol use, medication use, steatosis or steatohepatitis, and cirrhosis. Steatosis and cirrhosis are ruled out by the ultrasound. Other common health conditions, such as diabetes, heart disease, pancreatitis, hemolytic anemia and thyroid disease, can also cause liver transaminase elevations. Most liver diseases are characterized by greater ALT elevations than AST elevations except cirrohsis and alcohol abuse. ALT also rises in bile duct obstruction due to stone.
Raised alkaline phosphatase (The normal range is 44 to 147 IU/L (international units per liter).is often found in a growing child and at puberty. There are several bone disorders too that can raise this enzyme like rickets, osteomalacia, Paget’s disease of the bone, tumors, metastasis and recent fracture. An elevation in AP is often seen in cholestatic liver disease, bone disease, and occasionally with inflammatory bowel disease. In an otherwise healthy individual a rasied AP could be due to false positive test and the test should be repeated. If it is still high then other mentioned causes should be ruled out.
Please consult your PCP for primary examination followed by proper referral.
Take care!
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