I have received cortisone shots in my left knee at least three times and by trigger point injections into my right shoulder once. Whenever I have the shots in my knee, it literally swells up about 2 1/2 times its normal size and the pain is UNBEARABLE!!! Eventually, I hear a pop and the pain eases and the swelling goes away. When I received the trigger point injections in my shoulder, I had a little trouble breathing and felt like someone was sitting on my ribs for 2 or 3 days. Has anyone else had this problem and do you know if it is an allergy???