Are there any studies related to the long term use of pseudoephedrine-triprolidine? I took this over the counter medication for over 20 years. I am 40 years old now, and am experiencing many ailments, that the doctors can't identify cause. B12 deficiency, Diabetes, High Cholesterol, digestive issues, persistant rashes, depression, lethargy, heart issues, and the list goes on. I have looked all over the internet and I cannot find anything. Surely some studies have been done.