I just found the allergy page here ! I am going to post here and see if anyone has advice for me... My story begins on Thurs Jan 13, When I visited my primary care doctor for a cyst on my scalp that was draining. Also I belive a Gland? behind my right ear was swollen, in reaction to the scalp thing. I have a history of allergies to antibiotics, but as far as we knew I could tolerate Clindamycin. So she decide to prescribe me Clindamycin 300mg three times a day. I took the fist two doses okay, but then started feeling as if i might have a reation? The very next pill is the one that did it to me... as the advice nurse said if you can continue to take the medicine try to but that was about it for me. Started experiencing the same reaction I have had in the past to doxycycline, vancomycin, azithromycin, pencillin, keflex, and co-trimoxazole.I want to stress this reaction sometimes comes with a faint rash sometimes not at all. The nature of it being rather a burning sensation under the skin which is not visible, there is no hives, blisters sometimes not even a rash at all. The only thing that seems to help during this reaction is a steroid skin cream they gave me one time it works wonders ! But now I am day 3 going on 4 and I am going so crazy ! The pain and the burning is allmost too much to bear. these reactions in the past have went anywhere from 3 days to three weeks AFTER i stop taking the offending drug. I am so miserable right now, and the worst part is no one, not the doctors not my family nobody understands what im going through least of all me!? If it is a true allergic reaction, why no hives? rash? Just a very sick feeling, burning under the skin which is the worst on my hands, soles of my feet, lips eyes and girly parts. Benydryl seems to make little different, steroids seem to kinda help. On Sat evening I went to urgent Care where they gave me 20 mg prednisone and a perscription for 4 more tablets of the same, The Next night I went back in total Pain, to be told to take 2 of the tablets a day I have taken them and I am still burning !!! I am so sorry this post is so long, I think i just want to know if I am truly crazy or if anyone has ever heard of such a thing before? My Doctor called this morning and says what ever it is its not life threatening, If my throat closes up it would be different. My only consolation is my faith in God, and the fact in the past these reactions have allways resolved within a few weeks with no long term effects. But I wish to find an answer someday to find out if its a allergy or a hyper sensitive thing or what and what I can do about it. I am an active happy mom of a two yr old and I feel like my life is ruined I get bacterial infections and there is no help for me if the antibotics do this, and it is the most intense pain like a sunburn, omg. Anyway thank you for letting me vent Please any advice or Prayers I will gladly take I will try anything, thank you !