My sertraline tablets recently stopped working so well and the GP switched me straight on to fluoxetine. It was a complete nightmare, withdrawal from sertraline plus the side effects from fluoxetine took me to the most terrifying place. I then stopped all ssris and have not had any for 17 days. The first week was awful but then I started to improve, I seemed to get my energy back and I could go out and do things, this was short lived. Since Thursday I have been going downhill and am now in a pretty bad way again. I am physically exhausted, almost like I have the flu but without the fever. My mind is racing and I can’t sleep well, I just feel like there’s something awful wrong with me and im dying. When I wake in the morning I am hit with a huge sense of dread, nausea, palpitations, shaking. I hate going to bed in the evening because I know what the morning will bring. Is it normal to feel so physically unwell from it? I had Covid a month ago which probably hasn’t helped. I’m a 35yr old mum of two, I’m slim, my blood work is normal although I do often have low vitamin D and ferritin. I had a normal chest X-ray three weeks ago, my ecg showed st depression which was probably caused by me hyperventilating, I’ve had this before on an ecg and they have said it’s just a normal variant for me. I’ve been prescribed citalopram but I’m so scared of the side effects that I haven’t tried it yet. Is it normal to feel so physically fatigued and I’ll with anxiety and depression? Why did sertraline stop working after 3 years? Will ssri ever work for me again?