Okay, you say you suffered from anxiety for years but apparently managed it without medication. Then you started suffering symptoms, but it's not clear if the increase in anxiety occurred before you started feeling sick or after. Mono is a very serious illness that makes you really really sick. It can adversely affect the liver. It can definitely cause sweating, but probably more in the earliest stages. It does cause extreme fatigue. It's often hard to distinguish it from other illnesses -- way back when I was in college they thought I had mono but it turned out to be tonsilitis. Sometimes it takes the body awhile to manifest symptoms doctors can find; until then they can be very confused. As for the Lyme, it's possible you tested positive and the antibiotics worked and so you later tested negative. It's possible you never had it. It's possible you still have it. It's a very hard disease to diagnose and treat. There are two levels of Lyme -- the basic disease that is kind of like having the flu and the chronic version, which can feel like fibromyalgia. The problem here is that, and I know a certain person is going to chime in opposing this, you had some complications going on and your general doc was out of his league in trying to treat them. He should have sent you to that specialist before putting you on Celexa. It's pretty dumb to put you on any medication to treat symptoms before the bloodwork comes back. When it came back positive for Lyme, that disease causes every symptom you're complaining about. So does taking antibiotics. Right now your immune system is totally messed up and you're vulnerable to all kinds of things until (if) it recovers. Your beneficial organisms that protect you from bacterial and fungal infections and maintain your emotional system are probably in crisis and need to be replenished as best as possible -- you can help that by taking the best multi-spectrum probiotic in the refrigerated section of the best health food store in your area and also by eating foods that are very good food for probiotics, such as cultured or fermented foods like kim chi. Now, more bad news -- one of the most common side effects of Lexapro and Celexa, which are both made by the same company and have the same root ingredients basically, is night sweats. That's why a good doctor would never have put you on that if he thought you might be suffering from a disease state, and you were and are. Antidepressants can have both start-up and long-term side effects, and these effects start before the beneficial effects do. If bloodwork was called for, and it usually is a good idea to do that whenever someone has the kind of symptoms you were reporting because while anxiety can cause a lot of horrid stuff anxiety itself and the same horrid stuff can also be caused by a host of physiological problems, so it's good to eliminate them before deciding it's from anxiety. It appears the anxiety spike was caused in your case because you were very sick and with that underlying anxiety problem you had you reacted with additional anxiety. So if you have either Lyme or mono, both can take a long time to fully recover from. Time will take care of it if you're otherwise healthy and take good care of yourself and are young. So lastly, if you've been on the Celexa for two months, make sure you taper down on it slowly. Don't quit abruptly -- these meds are hard to stop. But it very well may be the cause of your night sweats. I got them from both Lexapro and Celexa, and again, they're a common side effect of those drugs. I really do have a horrible anxiety problem and so I dealt with it by taking a shower before going to bed but sometimes woke up sweating anyway and had to take another shower to be able to sleep. That usually worked for me, but given your illness situation, maybe not such a good idea for you right now. I'd go all the way to stopping the Celexa, get past your illness state, and when you're fully recovered and back to full strength for awhile, decide then if you want to use medication or therapy to tackle the anxiety. I'm basing this on your statement that you have dealt with this for years without meds, so you can probably go back to doing that for awhile. If you were able to do that, I'd suggest therapy for it rather than meds assuming when you recover fully from your illness you go back to not being so anxious that you can't function. I know this is long, but your situation is complex and you have a pretty severe possible set of illnesses that do take a while to recover from. This wouldn't be the optimal time to start adding side effects of antidepressants if you don't need them. If you do need them, if your anxiety isn't from the fear added by an illness that you will recover from after some patient time coddling yourself, that might be a different story. All the best.